- RecruitingPHASE3
A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism
This study is testing a new medicine, Baxdrostat, for people with high blood pressure caused by a condition called primary aldosteronism. We want to see if it's safe and helps lower blood pressure and balance hormones better than a dummy pill.
For: Primary HyperaldosteronismUnited States · Australia · Canada - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants with Resistant Hypertension.
This study is testing a new medication called Baxdrostat for people whose high blood pressure is difficult to control, even with several other medicines. We want to see if Baxdrostat can significantly lower blood pressure over 12 weeks compared to a dummy pill.
For: Resistant hypertension (rHTN) defined as blood pressure that remains higher than goal levels despite the use of at least 3 anti hypertensive drugs of different classes at maximum tolerated dose · including a diuretic.Bulgaria · Spain · Slovakia - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Efficacy and Safety of Baxdrostat in Participants with Uncontrolled Hypertension on Two or More Medications including Participants with Resistant Hypertension
This study is testing a new drug called Baxdrostat for people whose high blood pressure isn't controlled by their current medicines. It aims to see if Baxdrostat helps lower blood pressure and if it's safe to use, compared to a dummy pill.
For: Uncontrolled hypertension (uTHN) defined as blood pressure that remains higher than goal levels despite patients being treated with 2 anti-hypertensive agents · including a diuretic.Netherlands · Bulgaria · Denmark