- Ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
(22292) Randomized, non-blinded, two-way crossover study to assess bioequivalence between finerenone 2 x 20 mg tablets and 1 x 40 mg tablet in healthy male adult participants
This study looks at two different ways of taking a heart medicine, finerenone. Researchers want to check if two smaller tablets work the same way in the body as one larger tablet in healthy men. It's a study a bit like comparing different brands of the same medication.
For: Heart failure with left ventricular ejection fraction ≥40%Germany - Ongoing, recruitingTherapeutic confirmatory (Phase III)
(22267) A parallel-group, randomized, prospective, interventional, double-blind, multicenter global Phase 3 study to investigate the efficacy and safety of finerenone versus placebo, in addition to standard of care, in participants with chronic kidney disease and type 1 diabetes
This study is looking into a new medication called finerenone for people with long-term kidney disease caused by type 1 diabetes. We want to see if it works better than a dummy medicine (placebo) to slow down kidney damage over 6 months, alongside their usual care.
For: Chronic kidney disease associated with type 1 diabetes mellitusItaly · Germany · Denmark - Ongoing, recruitingTherapeutic confirmatory (Phase III)
(21177) A randomized, double-blind, placebo-controlled, parallel-group, multicenter Phase 3 study to investigate the efficacy and safety of Finerenone, in addition to standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kidney Disease
This study is looking into a new medication called Finerenone for people with long-term kidney disease that isn't caused by diabetes. It aims to see if the drug can slow down kidney disease progression and if it's safe to use, compared to a dummy pill.
For: Non-diabetic chronic kidney diseaseBulgaria · Denmark · Spain