- Ongoing, recruitingTherapeutic confirmatory (Phase III)
A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER, ADAPTIVE PHASE III TRIAL TO INVESTIGATE EFFICACY AND SAFETY OF VILOBELIMAB IN THE TREATMENT OF ULCERATIVE PYODERMA GANGRENOSUM
This study is testing a new medicine called Gohibic for people with a skin condition called ulcerative pyoderma gangrenosum. It compares Gohibic to other treatments or a dummy medicine to see if it helps heal the ulcers and reduces pain, with the aim of finding better ways to treat this condition.
For: ulcerative pyoderma gangrenosumBelgium · Hungary · Poland - Ongoing, recruitingTherapeutic confirmatory (Phase III)
Rapid rEcognition of COrticosteroid Resistant or sentive Sepsis - RECORDS A Multicentre Concealed‐Allocation Multi-arms Blinded Randomized Controlled Trial to Identify the Best Sepsis Population for Corticotherapy
This study, called RECORDS, is looking for better ways to treat serious infections (sepsis) in intensive care. It's comparing different steroid medicines, like hydrocortisone and betamethasone, to see which works best for patients and helps them recover faster.
For: Patients admitted to the ICU proven or suspected infection as the main diagnosis.France - Ongoing, recruitingTherapeutic confirmatory (Phase III)
HORNbILL. HydrOcortisone and fludRocortisoNe for critical ILLness-related corticosteroid insufficiency
This study looks at treating very unwell patients in intensive care who have a problem with their stress hormones. Researchers are testing if giving certain hormone medicines helps patients get off breathing machines and blood pressure support more quickly. It aims to improve recovery for those with this specific condition.
For: Critically ill patients suffering from CIRCIFrance