- RecruitingNA
Prediction in Silico of Pathological Response in a Prospective Cohort Study of Early Breast Cancer Patients
This study aims to better predict how well breast cancer treatments will work for patients with early-stage breast cancer. By collecting detailed information from patients, researchers hope to develop a tool to help doctors choose the best treatment for each person.
For: Breast CancerFrance - RecruitingNA
Virtual Reality Therapy to Improve Arthroplasty Outcomes
This study looks at whether Virtual Reality (VR) headsets can help people feel less anxious and manage pain better after a knee or hip replacement. VR uses a special headset to create a calming, 3D world with sounds and images to distract you. Researchers want to see if it improves how you feel after surgery.
For: Surgical · Anxiety · Pain ManagementUnited Kingdom - RecruitingNA
Prospective Monocentric Study Evaluating the Circulating NK Cells Phenotype and the ImmunoScore® in Patients With Non Metastatic Rectal Cancer
This study looks at new ways to treat non-spreading bowel cancer by using blood tests and special scores. It aims to see if we can better predict who will respond well to treatment and potentially avoid major surgery, improving life quality.
For: Rectal Cancer · Non Metastatic CancerFrance - RecruitingNA
Multi-parametric MRI Evaluation of Renal Graft Performance After Living Donor Donation.
This study uses advanced MRI scans to check how well kidneys from living donors work after transplant. We're looking at various factors like blood flow and oxygen levels in the donated kidney and the donor's remaining kidney to improve donor matching and long-term success.
For: Renal Insufficiency, ChronicFrance - RecruitingNA
Long-term Alterations of Host-microbiome Interactions and Cardiovascular and Respiratory Diseases Progression After Pneumonia
This study looks at how pneumonia affects your heart and lungs long-term. We want to understand why some people get heart problems after pneumonia and how we can better support them. It’s for people with or without current heart issues, including those who’ve had hospital-acquired pneumonia.
For: Hospital Acquired Pneumonia (HAP) · Cardiovascular and Respiratory DiseaseFrance - RecruitingNA
Impact of Bacterial Expression and Immune Response in the Severity of Pertussis
This study aims to understand why whooping cough (pertussis) is becoming more common and severe, especially in babies. We'll look at how the bacteria causing it are changing and how children's bodies fight the infection, hoping to find better ways to treat and prevent it.
For: Bordetella Pertussis, Whooping CoughFrance - Active not recruitingPHASE3
MEthotrexate Versus TOcilizumab for Treatment of GIant Cell Arteritis: a Multicenter, Randomized, Controlled Trial
This study compares two treatments, methotrexate and tocilizumab, for Giant Cell Arteritis (GCA). GCA causes inflammation in blood vessels, often affecting older adults. The aim is to find out if methotrexate is as effective as tocilizumab in preventing GCA flare-ups, but potentially with fewer side effects and lower cost.
For: Giant Cell ArteritisFrance - Recruiting
Validating Novel, Non-contrast Cardiac MRI Imaging in Haemodialysis Patients
This study looks at a new MRI scan for people on dialysis to measure heart scarring. We want to see if this new scan, called native T1 mapping, accurately shows how much scarring is really there. This could help us understand and treat heart problems in dialysis patients better.
For: End Stage Kidney Disease · Fibrosis MyocardialUnited Kingdom - Active not recruiting
Resistance to the Tyrosine Kinase Inhibitor Osimertinib and Pharmacokinetics in Non-small Cell Lung Cancer
This study looks at how a lung cancer drug called osimertinib works in the body and why it sometimes stops being effective. Researchers want to understand if different drug levels in the blood affect how well it works and if this could help prevent the cancer from coming back.
For: Lung CancerFrance - Not yet recruiting
Establishment of a Patient Library in Patients With Pruritus Sine Materia
This study aims to understand chronic itching better. We'll collect samples like blood and skin, and ask you to complete questionnaires to learn more about the causes of itching. This helps improve diagnosis and treatment.
For: Pruritus · Chronic Pruritus · ItchFrance - RecruitingNA
Single-center Prospective Longitudinal Study of Taste in Patients With Cognitive Disorders at Different Stages of Severity (Isolated Cognitive Complaint, Minor or Major Neurocognitive Alzheimer-type Disorders) by Analysis of Gustatory Evoked Potentials
This study looks at how your sense of taste changes if you have memory problems, from mild to more severe Alzheimer's disease. Researchers hope to find early signs of Alzheimer's by studying taste, which could help with earlier diagnosis and better care.
For: Cognitive DisordersFrance - RecruitingNA
Survival of Monocytes Collected From Patients With Atrophic AMD in Retinal Pigmented Epithelium Explants
This study looks at how immune cells (monocytes) from people with a type of age-related macular degeneration (AMD) called atrophic AMD survive on eye cells. We want to understand if these cells behave differently, as this could help find new treatments for this condition, which currently has no cure.
For: Age Related Macular DegenerationFrance - RecruitingNA
Cohort of Patients With Systemic Sclerosis Within the Framework of the RESO Reference Centre
This study looks at how scleroderma (a rare condition affecting skin and organs) changes over 5 years. Researchers collect blood and tissue samples to better understand this disease, as there is currently no cure. They hope to improve future treatments.
For: Scleroderma · Systemic SclerosisFrance - RecruitingNA
Evaluation of the Level of Expression of CD45RC on T Lymphocytes as a Predictive Biomarker of Acute Rejection After Renal Transplantation
This study looks at a special marker on blood cells (CD45RC on T-cells) in kidney transplant patients. We want to see if having high levels of this marker before a transplant can predict if the new kidney will be rejected, helping us improve care.
For: End-stage Renal DiseaseFrance