- AuthorisedTherapeutic use (Phase IV)
Inhaled corticosteroids in young children with episodic wheezing: a multicenter cluster RCT
This study looks at different inhalers to help young children who get wheezy sometimes. Researchers want to find the best way to control their symptoms and make them feel better, using medicines already available. It's about finding the easiest and most helpful treatments for these children.
For: Episodic expiratory wheezingNetherlands - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Randomized, Double-Blind, Double Dummy, Parallel Group, Multicenter 24 to 52 Week Variable Length Study to Assess the Efficacy and Safety of Budesonide, Glycopyrronium, and Formoterol Fumarate Metered Dose Inhaler (MDI) Relative to Budesonide and Formoterol Fumarate MDI and Symbicort® pressurised MDI in Adult and Adolescent Participants with Inadequately Controlled Asthma (KALOS)
This study is testing a new inhaler for adults with asthma that isn't well controlled. It compares a new triple-medicine inhaler to existing ones to see if it works better at preventing asthma attacks and improving breathing over 24-52 weeks.
For: Severe and inadequately controlled asthmaSpain · Romania · Hungary - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Randomized, Double-Blind, Double Dummy, Parallel Group, Multicenter 24 to 52 Week Variable Length Study to Assess the Efficacy and Safety of Budesonide, Glycopyrronium, and Formoterol Fumarate Metered Dose Inhaler (MDI) Relative to Budesonide and Formoterol Fumarate MDI and Symbicort® pMDI in Adult and Adolescent Participants with Inadequately Controlled Asthma (LOGOS)
This study is looking at new inhalers for adults with asthma that isn't well-controlled. It aims to see if a new combination inhaler works better than current ones to improve breathing and reduce asthma attacks.
For: Severe and inadequately controlled asthmaPortugal · Greece · Germany - RecruitingPHASE4
Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels
This study looks at how a common COPD medication (budesonide) affects people, depending on their eosinophil levels and lung germs. It aims to understand why some patients respond better than others to this treatment.
For: Chronic Obstructive Pulmonary DiseaseGermany · Netherlands · Spain