- Ongoing, recruitingTherapeutic exploratory (Phase II)
A multi-center, randomized, placebo- and active-controlled, parallel-group, 24-week proof of concept and dose-finding study to evaluate efficacy, safety, and tolerability of XXB750 in patients with heart failure
This study is looking into a new medication called XXB750 for people with heart failure. It hopes to see how well it works, what dose is best, and if it's safe compared to a dummy treatment or existing medicines.
For: Heart FailureNetherlands · Italy · Bulgaria - AuthorisedTherapeutic use (Phase IV)
NT-proBNP Selected PreventiOn of cardiac eveNts in a populaTion of dIabetic patients without A history of Cardiac disease; a prospective randomized trial
This study looks at how certain blood pressure and heart medications might help people with type 2 diabetes, who haven't had heart problems before, to avoid future heart issues. It focuses on a specific blood marker (NT-proBNP) to guide treatment.
For: Diabetes mellitus Type 2Spain · Austria - AuthorisedTherapeutic confirmatory (Phase III)
A phase 3 randomized, placebo-controlled, triple blind parallel-group study of candesartan in adults with episodic cluster headache (Episodic CandClus2)
This study is testing a new medicine, candesartan, to see if it can help people who get severe cluster headaches. Researchers want to know if it can reduce how often and how bad these headaches are.
For: episodic cluster headacheDenmark · Norway - AuthorisedTherapeutic confirmatory (Phase III)
A multicenter, phase 3, randomized, placebo-controlled, triple-blind crossover study of candesartan for prevention of chronic cluster headache (Chronic CandClus2)
This study looks at whether a medicine called candesartan can help people with ongoing cluster headaches — severe headaches that happen regularly. It compares candesartan with a dummy pill to see if it reduces how often and how bad these attacks are.
For: chronic cluster headacheNorway · Denmark