- AuthorisedTherapeutic confirmatory (Phase III)
BICCS - Beta-lactam Intermittent versus Continuous infusion and Combination antibiotic therapy in Sepsis
This study looks at different ways to give antibiotics to people with a serious infection called sepsis. Researchers want to see if continuous treatment or using different antibiotics together can help people recover better and reduce deaths in the first 30 days.
For: antibiotic therapy in SepsisFrance - AuthorisedTherapeutic exploratory (Phase II)
Early optimization of ceftazidine dosing regimen in critical care : FORTOPTIM_1
Researchers are looking at how to give ceftazidime, an antibiotic, to people with serious infections called sepsis. They want to find the best dose to make sure the medicine works well without causing side effects. This study aims to make treatment safer and more effective for very unwell patients.
For: sepsisFrance - AuthorisedTherapeutic use (Phase IV)
Defining Antibiotic Levels in Intensive care patients (DALI-2) protocol - A multi-national pharmacokinetic/pharmacodynamic cohort study to determine whether contemporary antibiotic dosing for critically ill patients achieves therapeutic exposures.
This study looks at how well antibiotics work in very sick patients. Researchers want to make sure these important medicines reach the right levels in the body to fight serious infections effectively and safely. It's about getting the dose just right.
For: Serious infections in critically ill patients treated with antibioticsFrance - AuthorisedTherapeutic use (Phase IV)
Phase IV, randomized, open label, parallel groups clinical trial for evaluating the early Stop of antibiotic Treatment in high-risk febrile neutropenic Oncohaematological Paediatric patients (e-STOP 2)
This study looks into safely stopping antibiotics early for children with cancer who get fevers due to low white blood cells. It compares two groups to see if ending antibiotic treatment sooner is just as safe as longer treatment for these children.
For: Infectious diseasesSpain - Ongoing, recruitingTherapeutic use (Phase IV)
SAFE study: Stopping Antibiotics after 3 days for the treatment of FEbrile Neutropenia in Haematology patients, a randomized open-label non-inferiority trial
For: Febrile neutropeniaBelgium