- Ongoing, recruitingTherapeutic use (Phase IV)
Understanding the Neurobiology of Pharmacologically-induced Acute Stress on Ethical Decisions
This study looks at how stress affects the choices people make, especially when faced with tough ethical decisions. Researchers are using common medicines to create temporary stress and then observing how participants think and decide in different situations.
For: Mimic an acute stress response in humans.Netherlands - Ongoing, recruitingPhase III and phase IV (Integrated)
Efficacy of Diltiazem to improve coronary microvascular dysfunction: a randomized clinical trial
This study called 'Diltiazem for Angina' is testing if a medicine called diltiazem can help people with angina by improving how their tiny heart blood vessels work. They want to see if it fixes at least one problem with these vessels without causing new ones.
For: AnginaNetherlands - AuthorisedTherapeutic confirmatory (Phase III)
Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery (CRPS-VITC)
This study is looking into whether taking Vitamin C for 6 months after upper limb (arm or hand) surgery can help prevent a condition called Complex Regional Pain Syndrome (CRPS). CRPS can cause severe and long-lasting pain.
For: Algoneurodystrophy CRPS type 1France - Ongoing, recruitingTherapeutic exploratory (Phase II)
Dasatinib and quercetin, a combination of senolytics to treat fibrotic non-alcoholic fatty liver disease; The TRUTH study
This study, called The TRUTH study, is looking at a combination of two drugs, dasatinib and quercetin, to treat a liver condition called non-alcoholic fatty liver disease (NAFLD) with scarring (fibrosis). Researchers want to see if this treatment can improve liver scarring over 21 weeks.
For: MASLD · NAFLDNetherlands - AuthorisedTherapeutic confirmatory (Phase III)
Prolonged corticosteroid therapy in scheduled cardiac surgery in intermediate/high-risk patients: a prospective multicenter randomized controlled double-blind placebo-controlled study
This study is looking at whether giving certain steroid medicines before and after heart surgery in people with higher risks helps prevent problems like kidney failure or lung issues. It aims to see if these medicines are safe and effective.
For: high /medium risk cardiac surgery · acute renal failureFrance