- Ongoing, recruitingTherapeutic use (Phase IV)
The OPTIMIzE study;OPen label multicenter randomized Trial comparing standard IMmunosuppression with tacrolimus and mycophenolate mofetil with a low exposure tacrolimus regimen In combination with everolimus in de novo renal transplantation in Elderly patients.
This study looks at new ways to give medicines after a kidney transplant to elderly patients. It compares standard treatment with a different combination of drugs to see which works best for protecting the new kidney and keeping patients healthy.
For: kidney transplantNetherlands · Belgium - Ongoing, recruitingPhase III and phase IV (Integrated)
Prospective Randomized trial of Everolimus replacing MMF/MP Acid by the RECOVAC consortium to increase VACcine response in kidney transplant patients
This study looks at how well kidney transplant patients respond to COVID-19 and shingles vaccines when their anti-rejection medication is changed. It compares two different drug treatment plans to see which one helps the body make more protective antibodies.
For: kidney transplantation · COVID-19 · Herpes ZosterNetherlands