CHLORURE DE SODIUM 0 clinical trials
9 indexed studies · 0 currently recruiting
- Ongoing, recruitingTherapeutic exploratory (Phase II)
Dose Study of Tranexamic Acid in Total Hip Replacement to Reduce Postoperative Hemoglobin Loss. A Phase 2 Randomized Double-blind Monocentric Study. The PRADO study
This study looks at how different doses of a medicine called tranexamic acid can help reduce blood loss during and after hip replacement surgery. It aims to find the safest and most effective amount to use, helping patients recover better.
For: Arthropathy of HipFrance - Ongoing, recruitingTherapeutic confirmatory (Phase III)
Does high-dose vitamin B3 supplementation prevent major adverse kidney events during septic shock? A multicenter randomized controlled study.
This study looks at whether a high dose of vitamin B3 can help prevent serious kidney problems in very sick patients called "septic shock." It compares vitamin B3 to a dummy treatment to see if it helps reduce deaths or the need for kidney dialysis.
For: adverse kidney events during septic shockFrance - AuthorisedTherapeutic confirmatory (Phase III)
Comparison of Landiolol versus standard of care for prevention of mortality in patients hospitalized for a septic shock with hypercontractlity: an open label prospective randomized study
This study compares a new medicine called Landiolol with usual treatment for very sick patients in intensive care with a serious infection (sepsis) and a fast, overworking heart. It aims to see if Landiolol can improve survival at 28 days for these patients.
For: patients hospitalized for a septic shock with hypercontractlityFrance - Ongoing, recruitingTherapeutic confirmatory (Phase III)
KETALGIA : Evaluation of the effectiveness of a ketamine infusion combined with magnesium sulfate in the treatment of chronic refractory cluster headache
This study is looking into whether a special drip (infusion) containing ketamine and magnesium could help people in the UK who suffer from very severe, ongoing cluster headaches. Researchers want to see if this treatment can reduce how often these painful headaches occur.
For: refractory chronic cluster headacheFrance - AuthorisedTherapeutic confirmatory (Phase III)
ASPAPY - Aspirin in acute pneumonia in the elderly: a multicenter, double-blind, randomized, placebo-controlled trial
This study is looking at whether aspirin can help older people with severe pneumonia. Researchers want to see if taking aspirin changes how many people die within 90 days after getting pneumonia, compared to a dummy drug.
For: acute pneumoniaFrance - Ongoing, recruitingTherapeutic confirmatory (Phase III)
Benefits on Post-operative Pain of Intravenous, Intraoperative, Tranexamic Acid Injection During Arthroscopic Shoulder Surgery.
This study is looking at whether a medicine called tranexamic acid can help reduce pain after shoulder surgery. Researchers will check if patients who receive it need less strong pain medication (morphine) in the first 24 hours after their operation.
For: Patient requiring shoulder arthroscopyFrance - AuthorisedPhase I and Phase II (Integrated)- Other
Phase 1 (sequential)/2a (parallel), double-blind, multicenter, randomized, controlled study to evaluate the safety and immunogenicity of two administrations of OVX033 sarbecovirus candidate vaccine, given intramuscularly (IM) at one-month interval, at three dose levels, in comparison to placebo, in subjects aged 18 years and older
This study is testing a new vaccine called OVX033 for sarbecoviruses, which include viruses like the one that causes COVID-19. Participants aged 18 and over will receive the vaccine or a dummy injection, to see how safe it is and how well it helps their immune system fight off these viruses.
For: Sarbecoviruses diseaseFrance - Ongoing, recruitingTherapeutic exploratory (Phase II)
Phase 2b, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy, immunogenicity and safety of one dose of OVX836 influenza vaccine 480μg, after intramuscular administration in healthy subjects aged 18-59 years
This study is testing a new flu vaccine called OVX836 in healthy adults aged 18 to 59. We want to see how well it prevents the flu, if it's safe, and how the body reacts to it after just one shot. It's a careful study comparing the vaccine to a dummy treatment.
For: Influenza diseaseFrance · Finland · Belgium - AuthorisedTherapeutic confirmatory (Phase III)
A multicentre, double-blind, randomized controlled trial of inhaled amikacin versus placebo in critically ill patients with ventilator-associated tracheobronchitis (AMIVAT)
This study looks at a new way to treat lung infections in very sick patients on breathing machines. We want to see if an inhaled antibiotic, amikacin, can stop a mild infection from becoming more serious compared to a dummy treatment.
For: Patients with ventilator-associated tracheobronchitisFrance