- RecruitingPHASE3
A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications
This study compares two ways to help young people (12-17) after a kidney transplant. It looks at changing medicine from one type (calcineurin inhibitor) to another (belatacept-based) and how well patients stick to their treatment. It aims to see which approach works best.
For: Renal Allograft RecipientsUnited States · Argentina · Belgium - RecruitingPHASE3
A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease
This study is looking at a new medicine called axatilimab, alongside standard steroids, for people with chronic graft-versus-host disease (cGVHD). It compares axatilimab with a dummy medicine (placebo) to see how well it works to treat this condition.
For: Chronic Graft-versus-host-diseaseUnited States · Australia · Austria - Active not recruitingPHASE2
A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease
This study looks at a new drug, axatilimab, combined with an existing one, ruxolitinib, to treat a condition called chronic graft-versus-host disease (cGVHD). It aims to see how safe and effective this new combination is.
For: Chronic Graft-versus-host-diseaseUnited States · Belgium · Canada - Active not recruitingPHASE3
Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP)
This study is looking at a new medicine called ianalumab for adults with a blood condition called ITP. We want to see if ianalumab, when given with standard treatment (steroids), can help keep platelet counts up. Half the participants will get ianalumab, and half will get a dummy medicine.
For: Primary Immune Thrombocytopenia (ITP)United States · Argentina · Australia