- Ongoing, recruitingHuman Pharmacology (Phase I)- Other
A Phase I, Open-Label Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics of a Single 3 mg Cytisinicline Dose
This early-stage study is looking at how a smoking cessation medicine called cytisinicline is handled by the body in people with kidney problems. We want to understand how kidney function, including dialysis, affects the medicine's levels in the body to ensure it's used safely.
For: Nicotine addictionPortugal · Spain - Ongoing, recruitingHuman Pharmacology (Phase I)- Other
A Four Way Crossover Thorough QT/QTc Study to Evaluate the Electrocardiographic Effects of Therapeutic and Supratherapeutic Doses of Cytisinicline in Healthy Smokers
This study is looking at how a new medicine, cytisinicline, affects the heart's electrical activity in healthy smokers. It wants to ensure the medicine is safe for your heart before it can be used for nicotine addiction.
For: Nicotine addictionPortugal - Ongoing, recruitingHuman Pharmacology (Phase I)- Other
A Phase 1 Study to Investigate the Effect of Food on the Bioavailability of a Single Cytisinicline 3 mg Tablet and Evaluation of the Pharmacokinetics of Multiple 3 mg Doses (Three Times Daily) in Healthy Adult Smokers
This study looks at a new medicine called Cytisinicline, which might help people stop smoking. It checks how the body handles the medicine when taken with food and when taken regularly. It's for healthy adult smokers.
For: No medical conditionPortugal