- Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, multicenter, open-label, randomized study to evaluate the efficacy and safety of fedratinib compared to best available therapy in subjects with DIPSS - intermediate or high-risk primary myelofibrosis, post-polycythemia vera myelofibrosis, or post-essential thrombocythemia myelofibrosis and previously treated with ruxolitinib
This study is comparing a new medicine, fedratinib, with other common treatments for people with a type of bone marrow disorder called myelofibrosis. It's for patients whose myelofibrosis has been treated before with another drug called ruxolitinib. We want to see how well fedratinib shrinks the spleen.
For: Primary myelofibrosis · post-polycythemia vera myelofibrosis · or post-essential thrombocythemia myelofibrosisBelgium · Italy · Hungary - AuthorisedTherapeutic exploratory (Phase II)
Exploratory Study of Ianalumab in Adults with Primary Immune Thrombocytopenia (ITP) and Warm-antibody Autoimmune Hemolytic Anemia (wAIHA) who Have Previously Benefited from Ianalumab (VAY RE-HIT)
This study looks at a medicine called ianalumab for adults with certain blood conditions (ITP or wAIHA). It wants to see if the medicine continues to work well for those who have used it before, aiming to understand its long-term benefits.
For: Immune thrombocytopenia (ITP) Warm autoimmune hemolytic anemia (wAIHA)Germany · Czechia · Belgium