- Ongoing, recruitingTherapeutic confirmatory (Phase III)
An Open-Label, Rater-Blind, Randomized, Multi-Center, Parallel-Arm, Active-Comparator Study to Assess the Efficacy and Tolerability of Ofatumumab 20mg SC monthly vs. First Line DMT - physician’s choice in the treatment of newly diagnosed RMS (STHENOS)
This study is testing a new way to treat multiple sclerosis (MS) called ofatumumab. It compares this new treatment to standard MS medications in people recently diagnosed with a specific type of MS called relapsing multiple sclerosis (RMS). The aim is to see which treatment works best to prevent MS attacks and stop the disease from getting worse.
For: relapsing multiple sclerosis (RMS)France · Germany · Italy - AuthorisedTherapeutic confirmatory (Phase III)
DESIRE MS: A prospective randomized non-inferiority trial comparing anti-CD20 maintenance versus De-Escalation Strategy In Relapsing-Remitting Multiple Sclerosis
This study compares different treatments for multiple sclerosis (MS) to see if a less intense approach is just as good as current treatments. It looks at how well people's MS is controlled over three years and checks for new symptoms or changes in brain scans.
For: Multiple sclerosisFrance - RecruitingPHASE3
Randomised Evaluation of COVID-19 Therapy
The RECOVERY trial looks at treatments for serious lung infections like pneumonia, including COVID-19. It helps doctors find the best ways to help hospitalised patients get better and reduce their risk of dying. Many treatments have been tested, and some have been found to be very helpful.
For: PneumoniaBelgium · Estonia · France