- Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Multi-center, Randomized, Double-blind Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy
This study is testing a new medicine, Aficamten, for people with a heart condition called obstructive hypertrophic cardiomyopathy. It compares Aficamten to a common medicine, Metoprolol, to see if it helps patients feel better and improve how well their heart works. Researchers want to know if it's safe and effective.
For: Symptomatic Obstructive Hypertrophic CardiomyopathyDenmark · Italy · Hungary - AuthorisedPhase III and phase IV (Integrated)
LEVOMEMS: Comparison of the Hemodynamic Profile of Dobutamine and Levosimendan in the Current Therapeutic Context
This study compares two common heart failure medicines, dobutamine and levosimendan, to see which works better for certain patients. Doctors will measure heart and lung pressure and how well the heart pumps blood after three months to understand their effects.
For: Heart failure patients with depressed left ventricular ejection fractionSpain - Ongoing, recruitingPhase III and phase IV (Integrated)
Adjunctive DobutAmine in sePtic cardiomyopathy with Tissue hypoperfusion: a randomized controlled multi-center trial
This study looks at treating severe blood poisoning (sepsis) that affects the heart. It tests a drug called Dobutamine to see if it helps improve organ function in people whose hearts aren't pumping enough blood, leading to tissue damage.
For: sepsisFrance