- Active not recruitingPHASE3
DOR/ISL in HIV-1 Antiretroviral Treatment-naïve Participants (MK-8591A-053)
This study is testing a new combination medicine, DOR/ISL, for people newly diagnosed with HIV-1 who haven't started treatment yet. It compares this new medicine to an existing treatment to see if it's as good at reducing the amount of HIV in the body.
For: HIV-1 InfectionUnited States · Argentina · Canada - Active not recruitingPHASE3
A Study of Doravirine/Islatravir (DOR/ISL, MK-8591A) for the Treatment of Human Immunodeficiency Virus 1 (HIV-1) Infection in Participants Who Previously Received DOR/ISL (MK-8591A-054)
This study looks at the safety of a two-in-one medicine called DOR/ISL for adults with HIV-1. It's for people who have already taken this medicine in other research studies. The main goal is to see how well people tolerate it over time.
For: HIV InfectionUnited States · Argentina · Australia - Active not recruitingPHASE3
A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF) (MK-8591A-052)
This study looks at a new two-drug HIV treatment, Doravirine/Islatravir (DOR/ISL), for people living with HIV-1 who are currently doing well on another common treatment, Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF). Researchers want to see if switching to the new treatment is as effective and safe.
For: HIV-1 InfectionUnited States · Australia · Chile - Active not recruitingPHASE3
A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Antiretroviral Therapy (ART) (MK-8591A-051)
This study looks at a new two-in-one medicine, Doravirine/Islatravir (DOR/ISL), for people with HIV-1 whose virus is already under control. It wants to see if switching to this new medicine is safe and works as well as their current treatment.
For: HIV-1 InfectionUnited States · Australia · Canada