- Active not recruiting
Anticoagulation in Patients With Venous Thromboembolism and Cancer
This study looks back at patient records to understand how different blood-thinning medicines work for people with cancer who have also had blood clots. It compares medicines like Apixaban, Rivaroxaban, and Dabigatran to see which are most effective and safe.
For: Neoplasms · EmbolismUnited Kingdom - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Randomized Study of Andexanet Alfa Compared to Usual Care in Patients Receiving a Factor Xa Inhibitor who Require Urgent Surgery or Procedure (ANNEXA-RS)
This study is comparing a new medication called Andexanet Alfa to usual care. It's for patients who are taking blood thinners (like apixaban, rivaroxaban, or edoxaban) and need urgent surgery. The aim is to see if Andexanet Alfa helps stop bleeding during their operation.
For: Reversal of anticoagulation effect in patients on a FXa inhibitor (apixaban · rivaroxaban · or edoxaban) who require urgent surgery or procedureFrance · Portugal · Spain - Active not recruitingPHASE4
EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF)
This study looks at whether a blood-thinning medicine called edoxaban can reduce the risk of stroke in people with an irregular heartbeat (atrial fibrillation) who have previously had bleeding in the brain. It compares edoxaban to not taking blood thinners.
For: Intracranial Hemorrhages · Atrial FibrillationUnited States · Argentina · Austria - Ongoing, recruitingTherapeutic use (Phase IV)
Determining the clinical relevance of the interaction between enzalutamide and the opioid morphine and the DOAC edoxaban to improve rational pharmacological care of patients with prostate cancer
This study looks at how a prostate cancer drug, enzalutamide, might affect other medicines like morphine (for pain) and edoxaban (a blood thinner). The aim is to make sure patients get the best and safest care when taking these drugs together.
For: Prostate cancerNetherlands