Envarsus 0.75 mg prolonged-release tablets clinical trials
6 indexed studies · 0 currently recruiting
- AuthorisedTherapeutic use (Phase IV)
Personalized tacrolimus treatment for pediatric kidney transplant recipients by using a dosing algorithm and a once-daily tacrolimus formulation
This study looks at a new way to give children who have had a kidney transplant a medicine called tacrolimus. It uses a special guide to help doctors give the right amount of medicine once a day, aiming to keep blood levels just right.
For: pediatric kidney transplant recipientsNetherlands - AuthorisedTherapeutic confirmatory (Phase III)
REVOLUTION; Randomized controlled trial comparing immediate versus extended release tacrolimus; reducing calcineurin inhibitor related toxicity in lung transplantation patients
This study looks at two different ways to give a medicine called tacrolimus to people who have had a lung transplant. The aim is to see if one way causes fewer side effects, especially problems with kidneys. It compares a standard capsule with a longer-acting tablet.
For: lung transplantationNetherlands - Ongoing, recruitingPhase II and Phase III (Integrated)
A multi-center interventional study to assess pharmacokinetics, effectiveness and tolerability of prolonged-release Tacrolimus after Paediatric Kidney Transplantation (Pro-Tac)
This study looks at a medicine called tacrolimus, given to children in the UK who have had a kidney transplant. It compares two versions of the medicine, Envarsus and Prograf, to see how well they work and if they have similar effects on the body.
For: Caucasian paediatric kidney transplant recipientsGermany - Ongoing, recruitingTherapeutic use (Phase IV)
Cognitive function after liver transplantation comparing Tacrolimus formulations
This study looks at how different types of a medicine called tacrolimus affect thinking and memory after a liver transplant. We want to see if one type is better for helping people with their attention and memory, checking how they feel and using simple tests.
For: ICD 10: Z94.4 Liver transplant statusGermany - Ongoing, recruitingTherapeutic use (Phase IV)
The OPTIMIzE study;OPen label multicenter randomized Trial comparing standard IMmunosuppression with tacrolimus and mycophenolate mofetil with a low exposure tacrolimus regimen In combination with everolimus in de novo renal transplantation in Elderly patients.
This study looks at new ways to give medicines after a kidney transplant to elderly patients. It compares standard treatment with a different combination of drugs to see which works best for protecting the new kidney and keeping patients healthy.
For: kidney transplantNetherlands · Belgium - Ongoing, recruitingTherapeutic use (Phase IV)
Personalized Use of Resources Study (PURE)
This study, PURE, looks at how different versions of a medicine called tacrolimus work in kidney transplant patients. It aims to see if a newer version can be given at a lower dose while still keeping the right amount of medicine in the body, potentially leading to fewer side effects and easier treatment.
For: kidney failure werefor need for kidney transplantNetherlands