- Ongoing, recruitingTherapeutic exploratory (Phase II)
A PHASE 2 STUDY OF ALX148 IN COMBINATION WITH PEMBROLIZUMAB IN PATIENTS WITH ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA (ASPEN-03)
This study looks at a new treatment called ALX148 combined with an existing cancer drug, pembrolizumab (Keytruda), for advanced head and neck cancer. Researchers want to see if this combination helps shrink tumours or stop them from growing.
For: metastatic or unresectable · recurrent HNSCCNetherlands · Belgium · Spain - Ongoing, recruitingTherapeutic exploratory (Phase II)
A PHASE 2 STUDY OF ALX148 IN COMBINATION WITH PEMBROLIZUMAB AND CHEMOTHERAPY IN PATIENTS WITH ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA (ASPEN-04)
This study is testing a new combination of medicines for people with advanced head and neck cancer. It combines an experimental drug called ALX148 with an existing treatment (pembrolizumab) and chemotherapy. Researchers want to see how well this new combination shrinks tumours.
For: metastatic or unresectable · recurrent HNSCCBelgium · Netherlands · Spain - Active not recruitingPHASE2
Evorpacept (ALX148) in Combination With Pembrolizumab in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03)
This study looks at a new drug, evorpacept, combined with an existing one, pembrolizumab, for advanced head and neck cancer. It aims to see if this combination works better than pembrolizumab alone for patients who haven't had treatment for advanced stages of their cancer. It's a Phase 2 trial, meaning it's still in earlier stages of testing.
For: Head and Neck Cancer · Head and Neck Squamous Cell CarcinomaUnited States · Australia · Belgium - Active not recruitingPHASE2
Evorpacept (ALX148) in Combination With Pembrolizumab and Chemotherapy in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-04)
This study looks at a new drug, evorpacept, combined with pembrolizumab and chemotherapy for advanced head and neck cancer. It aims to see if this new combination is effective for patients who haven't had treatment for their advanced disease.
For: Head and Neck Cancer · Head and Neck Squamous Cell CarcinomaUnited States · Australia · Belgium