- RecruitingNA
Fluoxetine on Emotional Experience (FLEX) Study
This study looks at how a common antidepressant, fluoxetine, affects anger in healthy young people. Researchers will compare fluoxetine to a dummy pill to see if it changes how participants react to anger-related situations and if this shows in their body.
For: Depression - Major Depressive Disorder · Irritability · DepressionUnited Kingdom - Not yet recruitingNA
Fluoxetine and Understanding Social Experiences
This study looks at how the antidepressant fluoxetine (Prozac) affects how young people aged 18-24 make social decisions. We want to understand how it impacts emotions, social interactions, and motivation. This helps us learn more about how antidepressants work in young adults.
For: Depression in Adolescence · Antidepressant Activity in Healthy Volunteers · Healthy Adult ParticipantsUnited Kingdom - Ongoing, recruitingPhase II and Phase III (Integrated)
A Phase 2/3, Multicenter, Randomized, Double blind, Placebo controlled Trial of the Safety and Efficacy of Flexible Doses of SEP 363856 as Adjunctive Therapy in the Treatment of Adults with Major Depressive Disorder.
This study is testing a new medicine, SEP-363856, for adults with major depression who are already taking antidepressants. It aims to see if adding this new medicine helps improve symptoms and if it's safe to use.
For: Adjunctive therapy to antidepressants for the treatment of major depressive disorder (MDD) in adults.Czechia · Bulgaria · Spain