- AuthorisedPhase III and phase IV (Integrated)
A randomized, double blind, double dummy, parallel group, multicenter clinical trial to evaluate the safety and clinical and microbiologic efficacy of oral fosfomycin calcium in adult womwn wiA th uUTI
This study is looking at a medicine called fosfomycin to treat simple urinary tract infections (UTIs) in adult women. We want to see how well it works to clear up symptoms and kill the bacteria causing the infection. It's a key step in understanding if this medicine is a good treatment option.
For: Uncomplicated urinary tract infection (uUTI)Spain - AuthorisedTherapeutic confirmatory (Phase III)
A multicenter randomized trial of fosfomycin versus ciprofloxacin for febrile neutropenia in hematologic patients: efficacy and microbiologic safety.
This study compares two antibiotics, fosfomycin and ciprofloxacin, for treating fever in patients with blood cancers when their immune system is weak after chemotherapy. It aims to see which one works better and is safer for preventing serious infections.
For: Post-chemotherapy neutropenia with high risk of developing infection in patients with acute leukemia undergoing induction · autologous or allogeneic hematopoietic stem cell transplantation (HSCT).Spain - AuthorisedTherapeutic use (Phase IV)
FOSFOMYCIN AS AN ORAL ALTERNATIVE THERAPY IN THE TREATMENT OF ACUTE BACTERIAL PROSTATITIS CAUSED BY MULTIDRUG-RESISTANT ESCHERICHIA COLI. PILOT STUDY
This study is looking at whether an antibiotic called fosfomycin can effectively treat a specific type of prostate infection in men. It's for men who have had some initial hospital treatment and have an infection caused by certain bacteria that are hard to treat with other medicines.
For: Prostatitis aguda bacteriana (PAB) por Escherichia coli multirresitente.Spain - AuthorisedTherapeutic use (Phase IV)
Defining Antibiotic Levels in Intensive care patients (DALI-2) protocol - A multi-national pharmacokinetic/pharmacodynamic cohort study to determine whether contemporary antibiotic dosing for critically ill patients achieves therapeutic exposures.
This study looks at how well antibiotics work in very sick patients. Researchers want to make sure these important medicines reach the right levels in the body to fight serious infections effectively and safely. It's about getting the dose just right.
For: Serious infections in critically ill patients treated with antibioticsFrance - AuthorisedTherapeutic confirmatory (Phase III)
Multicentre, randomised, double-blind, placebo-controlled clinical trial to confirm the efficacy, safety, and clinical impact of the mucosal bacterial therapeutic vaccine MV140 in women with non-complicated recurrent urinary tract infections (rUTIs).
This study is testing a new 'bacterial vaccine' called MV140 for women who get frequent urinary tract infections (UTIs). It aims to see if MV140 can help prevent new UTIs and if it's safe to use, compared to a dummy treatment.
For: Recurrent Non-Complicated Urinary Tract Infections (rUTIs).Portugal