- RecruitingPHASE2
A Modular Multi-Basket Trial to Improve Personalized Medicine in Cancer Patients (Basket of Baskets)
This study looks at new ways to treat advanced cancers by matching specific drugs to changes found in a patient's tumour genes. It tests three different drugs – atezolizumab, futibatinib, and amivantamab – to see how well they shrink tumours in different groups of patients.
For: Advanced Solid TumorFrance · Germany · Italy - RecruitingPHASE3
Personalized Medicine for Advanced Biliary Cancer Patients
This study looks at whether adding a special "targeted" drug after initial treatment for advanced bile duct cancer works better than continuing standard treatment. It customises treatment based on your tumour's unique features.
For: Biliary Tract NeoplasmsBelgium · France · United Kingdom - Enrolling by invitationPHASE2, PHASE3
Futibatinib in Patients Previously Enrolled in an Antecedent Futibatinib as Monotherapy or Combination Therapy.
This study is for cancer patients already taking the drug futibatinib in another study. It lets them continue treatment if it's helping and safe, ensuring ongoing care without interruption.
For: Advanced/Metastatic CancerUnited States · France · South Korea - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2 Study Evaluating Futibatinib (TAS-120) Plus Pembrolizumab in the Treatment of Advanced or Metastatic Urothelial Carcinoma
This study is looking at a new combination of medicines, futibatinib and pembrolizumab (Keytruda), for people with advanced bladder cancer. Researchers want to see if this treatment can shrink tumours or stop them from growing. It's a Phase 2 study, meaning it's focusing on how well the treatment works and its safety.
For: Advanced or Metastatic Urothelial CarcinomaFrance - Ongoing, recruitingTherapeutic confirmatory (Phase III)
MULTISARC : MOLECULAR PROFILING OF ADVANCED SOFT-TISSUE SARCOMAS. A phase III study
This study looks at new ways to treat advanced soft tissue sarcoma, a type of cancer. It uses special tests to check for changes in cancer cells and aims to find the best medicine for each person, making sure these tests are practical and quick enough.
For: Unresectable locally advanced and/or metastatic soft-tissue sarcomaFrance - RecruitingPHASE1, PHASE2
European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors
This study is for children and young people with cancer that hasn't responded to usual treatments. It tests new medicines that target specific changes in cancer cells, aiming to find the right dose and see if they help. The goal is to find better ways to treat childhood cancer.
For: Pediatric CancerDenmark · France · Italy