Ifinatamab deruxtecan clinical trials
5 indexed studies · 4 currently recruiting
- RecruitingPHASE3
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
This study is testing a new medicine, ifinatamab deruxtecan (I-DXd), for men with advanced prostate cancer that has spread and isn't responding to hormone therapy. We want to see if I-DXd helps men live longer and keeps their cancer from growing compared to standard chemotherapy.
For: Prostate Cancer · Prostatic NeoplasmsUnited States · Argentina · Australia - RecruitingPHASE1, PHASE2
A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)
This study is testing new treatments, alone or in combination, for advanced prostate cancer that has spread and no longer responds to hormone therapy. Researchers want to see if these treatments are safe and effective in helping men with this condition.
For: Castration-Resistant Prostatic Cancer · MetastasisUnited States · Argentina · Australia - RecruitingPHASE3
A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)
This study looks at a new drug, ifinatamab deruxtecan, for people with advanced oesophageal cancer that has already been treated. We want to see if it works better and is safer than standard chemotherapy for patients whose cancer has grown after previous treatments.
For: Esophageal Squamous Cell CarcinomaUnited States · Belgium · China - AuthorisedPhase I and Phase II (Integrated)- Other
LIGHTBEAM-U01 Substudy 01D: A Phase 1b/2 Substudy to Evaluate the Safety and Efficacy of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors
This study looks at a new medicine, Ifinatamab Deruxtecan, for children aged 1 month to under 12 years with certain cancers that haven't responded to other treatments. It aims to see how safe it is and if it helps shrink tumors or stop them from growing.
For: Neoplasm malignantFrance · Spain · Sweden - RecruitingPHASE3
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
This study is looking at a new medicine called ifinatamab deruxtecan (I-DXd) for small cell lung cancer that has come back. It compares I-DXd to standard treatments to see if it works better and is safe.
For: Small Cell Lung CancerUnited States · Australia · Austria