lactose monohydrate clinical trials
9 indexed studies · 0 currently recruiting
- Ongoing, recruitingTherapeutic use (Phase IV)
European Randomised Clinical Trial on mPOX Infection (EPOXI)
This study, EPOXI, is looking at how a capsule called tecovirimat (or a dummy capsule) helps adults with monkeypox. Doctors want to see how quickly skin rashes and other problems get better to find the best ways to treat the infection.
For: MonkeypoxNetherlands · France · Portugal - Ongoing, recruitingHuman Pharmacology (Phase I)- Other
A Multiple Ascending Dose Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MK-7602 in Healthy Participants
This study is looking at a new medicine called MK-7602 for malaria. It's an early-stage trial to check how safe it is, if people can tolerate it well, and how the body handles the medicine in healthy volunteers. It will help us understand if it's safe to test further for malaria.
For: MalariaBelgium - Ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A Single Ascending Dose Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MK-1403 in Healthy Male Participants
This early-stage study is looking at a new medicine called MK-1403 for a condition called atherosclerosis, which is a build-up in your arteries. We want to see how safe it is and how the body handles it in healthy men. It's the first time this medicine is being given to people.
For: AtherosclerosisBelgium - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Multicenter, Extension Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Two Doses of Linsitinib in Subjects with Active, Moderate to Severe Thyroid Eye Disease (TED)
This study is looking at a new medicine called linsitinib for people with a condition called Thyroid Eye Disease (TED). It wants to see how well it works and if it's safe. It's a follow-up to an earlier study, checking if the medicine helps reduce bulging eyes over time.
For: Thyroid Eye DiseaseSpain · Italy - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2b, Randomized, Double-Mask, Placebo-Controlled, Study to Evaluate the Safety, Pharmacokinetics and Efficacy of Linsitinib in Subjects with Active, Moderate to Severe Thyroid Eye Disease (TED)
This study is testing a new tablet medicine called linsitinib for people with moderate to severe Thyroid Eye Disease (TED). Researchers want to see if it's safe and helps improve bulging eyes after 24 weeks, compared to a dummy tablet.
For: Disease (TED)Italy · Spain - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A MULTICENTER, PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF SPIRONOLACTONE FOR THE TREATMENT OF ACTIVE RHEUMATOID ARTHRITIS (RA) - ALDORA
This study, called ALDORA, is looking at whether a common medicine called spironolactone could help people with rheumatoid arthritis (RA). It’s comparing spironolactone to a dummy pill to see if it reduces RA symptoms and improves heart health without causing too many side effects.
For: RHEUMATOID ARTHRITISGermany · France - Ongoing, recruitingTherapeutic use (Phase IV)
Simvastatin in the Prevention of Recurrent Pancreatitis, a Triple Blind, Randomized Controlled Trial.
This study is looking at whether a common medicine called simvastatin can help stop pancreatitis from coming back. Pancreatitis is when your pancreas gets inflamed. Researchers want to see if taking simvastatin can reduce how often people get this condition again.
For: Recurrent pancreatitisSpain - Ongoing, recruitingTherapeutic exploratory (Phase II)
Efficacy and safety of riociguat (MK-4836) in incipient pulmonary vascular disease as an indicator for early pulmonary arterial hypertension Double-blind, randomized, multicenter, multinational, placebo-controlled phase IIa study
This study is testing a new medicine called riociguat for a condition where blood vessels in the lungs become narrow. Researchers want to see if the medicine can help improve blood flow and if it's safe for people with early signs of this lung condition.
For: Pulmonary vascular diseaseFrance · Germany · Austria - AuthorisedTherapeutic confirmatory (Phase III)
Duration of Dual Anti-Platelet Therapy in Chronic Limb Threatening Ischemia after Distal Revascularization: a randomized, double-blind trial PALADIN [PeripherAL Arterial DIsease Network] -DAPTCLTI
This study looks at how long people with severe leg circulation problems should take a blood-thinning medicine called clopidogrel after surgery. It aims to see if taking it for different lengths of time changes their risk of needing another amputation or dying.
For: CLTI defined as Rutherford category 4 or 5France