Leflunomide 20mg/Placebo clinical trials

Leflunomide and Hydroxychloroquine combination therapy for primary Sjögren’s Syndrome; RepurpSS-II study

This study, called RepurpSS-II, is looking at how a combination of two existing medicines, Leflunomide and Hydroxychloroquine, might help people with primary Sjögren's Syndrome. Researchers want to see if these drugs can reduce disease activity and improve symptoms like dryness compared to a dummy pill.