- Ongoing, recruitingPhase III and phase IV (Integrated)
DPDIMP#1-trial: Impact of DPYD gene test on the safety and efficacy of fluoropyrimidine therapy
This study looks at how a gene test can make common cancer medicines for breast and colon cancer safer and work better. We're testing different forms of these medicines and checking how they move through the body to find the best and safest ways to treat patients.
For: Breast cancer · Colon cancerFinland - AuthorisedTherapeutic use (Phase IV)
Lantiolihaspuudutuksen vaikutus munuaisen poistoleikkauksen jälkeiseen kivun hoitoon ja toipumiseen
This study is looking at different ways to help with pain after kidney cancer surgery. It's testing if a nerve block, using medicines like ropivacaine and dexamethasone, can reduce the amount of strong pain medicine (opiates) people need within the first 24 hours after their operation. It also checks how long it takes for a person to ask for pain relief.
For: Renal cancerFinland - AuthorisedTherapeutic confirmatory (Phase III)
A single group treatment, phase 4, study to assess the effect of 1 dose with oxymetazoline nasal spray(Otrivin®) on physical capacity of males and females aged 18 and 64 years suffering from Chronic Obstructive Pulmonary Disease (COPD)
This study looks at how a nose spray (Otrivin) might help people with a lung condition called COPD. It checks if using the spray can improve how far they can walk, aiming to make breathing and activity easier.
For: Chronic Obstructive Plumonary Disease (COPD)Norway - AuthorisedTherapeutic use (Phase IV)
Premedication for Less Invasive Surfactant Administration (LISA-Med)
This study looks at giving tiny babies medicine before a procedure called LISA (Less Invasive Surfactant Administration). LISA helps babies with breathing problems by putting medicine into their lungs. The study wants to see if this 'pre-medicine' helps prevent any problems during the LISA procedure.
For: respiratory distress syndrome · surfactant treatment · premedicationFinland - AuthorisedTherapeutic use (Phase IV)
Post-operative analgesia and spinal block duration following total hip arthroplasties - comparison of single-shot intrathecal ropivacaine, and bupivacaine: a randomized, double blinded controlled study
This study compares two common pain medications, ropivacaine and bupivacaine, used in spinal injections for hip replacement surgery. Researchers want to see which one helps people recover sensation and movement faster after the operation, and how well they control pain.
For: Hip osteoarthrosis and postoperative painFinland - AuthorisedTherapeutic confirmatory (Phase III)
International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 - A Randomized Phase III Study Conducted by the Resistant Disease Committee of the International BFM Study Group - IntReALL BCP 2020
This study looks at new ways to treat children with a type of blood cancer called B-cell acute lymphoblastic leukaemia, which has come back after earlier treatment. It compares different drug combinations to find the most effective and safest options for them.
For: Relapsed Acute Lymphoblastic Leukemia (ALL)Netherlands · Czechia · Italy - AuthorisedTherapeutic confirmatory (Phase III)
LIBRETTO: Stimulan™ Local Antibiotic Delivery System Versus 4-Week Systemic Antibiotic Therapy for Diabetic Foot Osteomyelitis – A Prospective, Randomized, Controlled Trial
This study is looking at better ways to treat a serious foot infection called diabetic foot osteomyelitis. It compares a new local antibiotic treatment system with standard antibiotic pills or injections to see which is more effective at healing the infection and preventing its return.
For: Diabetic Foot OsteomyelitisFinland - AuthorisedTherapeutic confirmatory (Phase III)
Tranexamic Acid in Hind and Midfoot Arthrodesis Surgery: A Multicentre, Randomized, Placebo-Controlled Trial (TRASH Trial)
This study looks at whether a medicine called tranexamic acid can help prevent infections after foot and ankle surgery. We want to see if it reduces the number of wound infections and other problems over one year, compared to a dummy treatment.
For: Deformity · OsteoarthritisFinland