- Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Multicenter, Parallel group, Double-blind, Placebo-controlled, Randomized, Efficacy and Safety Study of Nicotine Freshmint Mouthspray in E-cigarette Users Willing to Quit
This study is testing if a nicotine mouth spray can help people who use e-cigarettes to stop vaping. It compares the spray to a dummy spray over a year to see how well it works and if it's safe.
For: Vaping cessation in e-cigarette usersGermany - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A prospective, randomized, double-blind placebo-controlled multicentre trial with mannan-conjugated birch pollen allergoids administered subcutaneously to adolescents and adults with birch pollen-induced allergic rhinitis or rhinoconjunctivitis.
This study is looking into a new treatment for birch pollen allergy. It compares a new vaccine-like medicine given by injection to a dummy treatment. The aim is to see if the new medicine can help reduce symptoms like sneezing and itchy eyes during pollen season.
For: birch pollen-induced allergic rhinitis birch pollen-induced allergic rhinoconjunctivitisGermany - AuthorisedTherapeutic exploratory (Phase II)
Antisense Oligonucleotide Eye Drops against IRS-1 to Optimize Pretransplant Lymphangio-regression Prior to High-Risk Keratoplasty (Olisens-Precon)
This study is testing new eye drops called OLISENS for adults with specific eye damage before a high-risk cornea transplant. The aim is to reduce abnormal blood vessels in the eye, which may improve transplant success. It's a phase II trial to check safety and how well it works.
For: Pathologically prevascularized corneas due to herpetic keratopathy prior to “high-risk” corneal transplantation (keratoplasty)Germany