Treatment

Lucerastat clinical trials

4 indexed studies · 2 currently recruiting

RecruitingPHASE3
A Study to Learn How Well Lucerastat Works and How Safe it is in Untreated Adult Male Participants With Fabry Disease
This phase 3 clinical trial is looking at an experimental medicine called lucerastat for men with Fabry disease. Researchers want to see if taking lucerastat every day safely lowers the buildup of harmful fatty substances in the kidneys in men who are not currently receiving other Fabry treatments.
For: Fabry Disease
United States · Canada · France
Active not recruitingPHASE3
A Study to Evaluate the Long-term Safety and Tolerability of Lucerastat in Adult Subjects With Fabry Disease
This clinical trial looks at the long-term safety of an oral medicine called lucerastat for adults with Fabry disease. It is open to people who have already finished an earlier six-month trial. Researchers want to find out how safe the medicine is when taken over several years.
For: Fabry Disease
United States · Australia · Austria
AuthorisedTherapeutic confirmatory (Phase III)
A multicenter, open-label, single-arm, baseline-controlled trial to assess the efficacy and safety of lucerastat in treatment-naïve/pseudo-naïve adult male participants with Fabry disease
This study tests a medicine called lucerastat for adult men with Fabry disease. Fabry disease causes a fatty substance to build up in the kidneys and blood vessels. Researchers want to see if taking lucerastat for 18 months is safe and helps clear this fat from the kidneys.
For: Fabry disease
Germany · France
RecruitingTherapeutic confirmatory (Phase III)
A multi-center, open-label, uncontrolled, single-arm, extension study to determine the long-term safety and tolerability of oral lucerastat in adult subjects with Fabry disease.
This study looks at a daily oral medicine called lucerastat for adults with Fabry disease. Researchers want to find out how safe the medicine is and how well people tolerate it over a longer time. Everyone who takes part receives the active medicine, with no dummy pills used.
For: Fabry disease
Austria · France · Germany

A Study to Learn How Well Lucerastat Works and How Safe it is in Untreated Adult Male Participants With Fabry Disease

A Study to Evaluate the Long-term Safety and Tolerability of Lucerastat in Adult Subjects With Fabry Disease

A multicenter, open-label, single-arm, baseline-controlled trial to assess the efficacy and safety of lucerastat in treatment-naïve/pseudo-naïve adult male participants with Fabry disease

A multi-center, open-label, uncontrolled, single-arm, extension study to determine the long-term safety and tolerability of oral lucerastat in adult subjects with Fabry disease.

A multi-center, open-label, uncontrolled, single-arm, extension study to determine the long-term safety and tolerability of oral lucerastat in adult subjects with Fabry disease.