magnesium stearate clinical trials
10 indexed studies · 0 currently recruiting
- Ongoing, recruitingTherapeutic exploratory (Phase II)
A Randomized, Double-blind, Placebo-controlled, Repeat-dose, Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients with Diffuse Cutaneous Systemic Sclerosis [HZNP-HZN-825-301]
This study is testing a new medicine, Fipaxalparant, for people with a serious skin condition called diffuse cutaneous systemic sclerosis. It aims to see if the medicine can improve lung function and other symptoms over about a year.
For: Diffuse Cutaneous Systemic SclerosisRomania · Austria · Germany - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase IIb Two-cohort, Randomised, Placebo-controlled, Double-blind, Multi-centre, Dose-ranging Study of AZD5462 in Stable Patients with Chronic Heart Failure
This study is testing a new medicine, AZD5462, for people with long-term heart failure. Researchers want to see if it improves how well the heart pumps, using ultrasound scans. It's a key step to understanding if this medicine could help patients.
For: Chronic Heart FailureBulgaria · Czechia · Poland - Ongoing, recruitingTherapeutic exploratory (Phase II)
The COlchicine HypERtENsion Trial
This study is looking at whether a medicine called Colchicine can help people with high blood pressure and heart problems. Researchers will check changes in how stiff people's arteries are after taking the medicine for six months, compared to a dummy pill.
For: Cardiovascular disease · HypertensionDenmark - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2 Theranostic Trial Evaluating the Effects of Thiethylperazine in Patients Diagnosed with an Early Stage of Alzheimer's disease
This study is looking into a new treatment for early Alzheimer's disease. It's testing if a medicine called thiethylperazine can slow down changes in the brain linked to Alzheimer's, using special brain scans and blood tests.
For: Newly diagnosed early-to-mild dementia due to Alzheimer's DiseaseGermany - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-0616 in Adults With Hypercholesterolemia
This study is looking at a new medicine, MK-0616, for adults with high cholesterol. It compares the new medicine to a dummy pill to see if it lowers 'bad' cholesterol and how safe it is over 24 weeks. This helps us understand if MK-0616 could be a new treatment option.
For: HypercholesterolemiaItaly · Spain · Germany - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2b Randomized, Double-blind, Placebo-controlled, Repeat-dose, Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects with Idiopathic Pulmonary Fibrosis
This study is testing a new medicine, Fipaxalparant, for a lung condition called Idiopathic Pulmonary Fibrosis (IPF). Researchers want to see if it's safe and helps improve lung function over one to two years compared to a dummy pill.
For: Idiopathic Pulmonary FibrosisFrance · Poland · Netherlands - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A MULTICENTER, PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF SPIRONOLACTONE FOR THE TREATMENT OF ACTIVE RHEUMATOID ARTHRITIS (RA) - ALDORA
This study, called ALDORA, is looking at whether a common medicine called spironolactone could help people with rheumatoid arthritis (RA). It’s comparing spironolactone to a dummy pill to see if it reduces RA symptoms and improves heart health without causing too many side effects.
For: RHEUMATOID ARTHRITISGermany · France - AuthorisedTherapeutic confirmatory (Phase III)
A randomized double-blind placebo-controlled study with ASA treatment in colorectal cancer patients with mutations in the PI3K signaling pathway
This study looks at whether a daily aspirin-like tablet helps people with certain types of bowel cancer (colon or rectal cancer) that have specific gene changes. It compares the tablet to a dummy pill to see if it stops the cancer from coming back.
For: Colon and rectal cancer tumor stage II-III · tumor with somatic alterationsin PIK3CA · PIK3R1 or PTENFinland · Sweden · Denmark - AuthorisedTherapeutic confirmatory (Phase III)
Single-blinded randomized investigator-initiated controlled trial to assess the efficacy of colchicine to treat patients with cardiomyopathy with myocarditis (chronic inflammatory cardiomyopathy) – Trial and Registry to study the role of genotype environment interaction in Chronic myocarditis and inflammatory cardiomyopathies with ventricular pro-arrhythmic and heart failure phenotypes (PNRR-MAD-2022-12376225)
This study is looking at whether a medicine called colchicine can help people with an inflammatory heart condition. It aims to see if the medicine can prevent the condition from getting worse and help improve heart health over six months.
For: Inflammatory cardiomyopathyItaly - Ongoing, recruitingTherapeutic exploratory (Phase II)
Efficacy and safety of riociguat (MK-4836) in incipient pulmonary vascular disease as an indicator for early pulmonary arterial hypertension Double-blind, randomized, multicenter, multinational, placebo-controlled phase IIa study
This study is testing a new medicine called riociguat for a condition where blood vessels in the lungs become narrow. Researchers want to see if the medicine can help improve blood flow and if it's safe for people with early signs of this lung condition.
For: Pulmonary vascular diseaseFrance · Germany · Austria