- AuthorisedTherapeutic use (Phase IV)
Acute appendicitis and microbiota – etiology and effects of the antimicrobial treatment - MAPPAC
This study looks at how antibiotics for appendicitis affect the helpful germs (microbiota) in your gut. It aims to see if certain gut germs are linked to more serious appendicitis and how different antibiotics change them.
For: Uncomplicated acute appendicitis · Complicated acute appendicitisFinland - RecruitingPHASE2, PHASE3
Finding the Optimal Regimen for Mycobacterium Abscessus Treatment
This study, called FORMaT, is looking for the best ways to treat a serious lung infection called Mycobacterium abscessus (MABS-PD). It tests different medicines to find the most effective and safest treatments, aiming to improve how people with this condition live.
For: Pulmonary Disease Due to Mycobacteria (Diagnosis)Australia · Denmark · Israel - RecruitingNA
Effect of Hyperglycaemia and Moxifloxacin on QTc Interval in T2DM
This study looks at how high blood sugar and the antibiotic moxifloxacin affect the heart's electrical rhythm in people with type 2 diabetes. Researchers want to see if moxifloxacin's effect on heart rhythm is worse when blood sugar is high or insulin is low, to improve patient safety.
For: Diabetes Type 2 · Hyperglycaemia (Diabetic) · QT Interval, Variation inUnited Kingdom - AuthorisedTherapeutic use (Phase IV)
Oral Antibiotic Outpatient Therapy vs. Placebo in the Treatment of Uncomplicated Acute Appendicitis: a Randomized Double-blind Placebo-controlled Noninferiority Trial APPAC IV
This study looks at whether antibiotics alone can treat mild appendicitis in adults, avoiding surgery. Half the patients get a common antibiotic, moxifloxacin, and the other half get a dummy pill (placebo). Doctors will check if the antibiotics successfully resolve the appendicitis without an operation.
For: Uncomplicated acute appendicitisFinland - AuthorisedTherapeutic use (Phase IV)
AIR. ANTIBIOTIC THERAPY IN RESPIRATORY TRACT INFECTIONS A controlled randomized, open label, multicenter, non-inferiority trial evaluating an individualized antibiotic treatment duration based on patient clinical response, evaluated through connected devices, for suspected community acquired pneumonia in the community setting
This study, called AIR, is looking at the best way to use antibiotics for chest infections (pneumonia). It compares different lengths of antibiotic treatment to see which works best, aiming to reduce how many antibiotics patients need.
For: Community acquired pneumonia (CAP)France - AuthorisedTherapeutic use (Phase IV)
Optimizing the antibiotic treatment of uncomplicated acute appendicitis: a prospective randomized multicenter study
This study looks at different antibiotic treatments for mild appendicitis. Researchers want to see which antibiotics work best to avoid surgery and prevent the appendicitis from returning for at least a year. It's for adults aged 18 and over.
For: Uncomplicated acute appendicitisFinland - AuthorisedTherapeutic confirmatory (Phase III)
Feasibility of the Application of a new Six-month Treatment for multidrug-resistant tuberculosis (MDR-TB) patients in France (FAST-MDR)
This study, called FAST-MDR, is looking at a new, shorter 6-month treatment for a severe type of tuberculosis (TB) that is hard to treat with usual medicines. It aims to see if this new treatment works as well as, or better than, older treatments for adults in France.
For: Patients diagnosed at the study sites with rifampicinresistant tuberculosis during the recruitment period will be evaluated for study inclusion.France