- Ongoing, recruitingTherapeutic confirmatory (Phase III)
Graft vs Host Disease Prophylaxis in unrelated donor transplantation: a randomized clinical trial comparing PTCY vs ATG
This study compares two ways to prevent a serious complication called graft-versus-host disease (GvHD) after a certain type of blood stem cell transplant. It aims to find out which method helps people live longer and stay healthier after their transplant.
For: Graft Vs Host Disease Peripheral Blood Stem Cell Transplantation AML MDS MDS/MPN CMMLGermany - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase III, Randomized, Placebo-controlled, Double-blind, Multi-center, International Study of Durvalumab Given Concurrently with Platinum-based Chemoradiation Therapy in Patients with Locally Advanced, Unresectable Non-small Cell Lung Cancer (Stage III) (PACIFIC2)
This study looks at a new drug called Imfinzi for people with a type of lung cancer that has spread nearby but can't be removed by surgery. It aims to see if Imfinzi, along with standard treatments like chemotherapy and radiation, helps people live longer and keeps the cancer from growing.
For: Patients with Locally Advanced · Unresectable Non-small Cell Lung Cancer (Stage III)Poland · Hungary - AuthorisedTherapeutic use (Phase IV)
Safety and efficacy of steering of immunosuppression based on BKPyV-specific T cells in case of BK Polyomavirus (BKPyV) DNAe- mia after kidney transplantation
This study looks at how well a new approach to adjusting medicines helps control a common virus called BK Polyomavirus (BKPyV) in people who have had a kidney transplant. The goal is to find the best way to keep the new kidney healthy.
For: BK Polyomavirus DNAemia after kidney transplantationGermany