- Ongoing, recruitingHuman Pharmacology (Phase I)- Other
Relative bioavailability of two different formulations of nerandomilast and investigation of the food effect on new formulation following oral administration in healthy adult male and female subjects (an open-label, randomised, single-dose, three-way crossover trial)
This study looks at a new medicine called nerandomilast. We want to see how two different forms of this medicine are absorbed by the body. We'll also check if food changes how a new form of it works, helping us understand the best way to take it.
For: Healthy volunteer trialGermany - RecruitingPHASE3
A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases
This study looks at a new medicine, nerandomilast, for people with lung scarring (fibrosis) linked to rheumatic diseases. It aims to see if nerandomilast improves lung function when standard treatments haven't helped. Participants take tablets for several months, with regular check-ups.
For: Interstitial Lung Diseases · Systemic Autoimmune Rheumatic Diseases Associated Interstitial Lung DiseasesUnited States · Australia · Austria - Not yet recruitingPHASE3
A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)
This study looks at a new medicine called Nerandomilast for children and young people aged 2 to 17 with a lung condition called interstitial lung disease (ILD). We want to see if it's safe, how the body uses it, and if it helps improve their health.
For: Fibrosing Interstitial Lung DiseaseUnited States · Argentina · Belgium - RecruitingPHASE3
A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis
This study investigates if a new drug, nerandomilast, can slow down lung changes in people aged 40+ with a family history of lung scarring (pulmonary fibrosis) and early changes seen on a lung scan. Participants receive either the drug or a dummy pill.
For: Familial Pulmonary Fibrosis · Interstitial Lung Abnormalities · Interstitial Lung DiseasesUnited States · Argentina · Australia - RecruitingPHASE3
A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast
This study looks at a long-term treatment called nerandomilast for people with pulmonary fibrosis. It's for those who've used it in a past study. We'll see how safe and effective it is over time, checking if it helps lung function and slows down the disease.
For: Idiopathic Pulmonary Fibrosis · Progressive Pulmonary FibrosisUnited States · Argentina · Australia