- Active not recruitingPHASE3
Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS
This study looks at the long-term safety and effectiveness of a medicine called ofatumumab for people with relapsing MS. It also checks how well vaccines work in people taking this medicine, including those for flu, pneumonia, tetanus, and COVID-19.
For: Relapsing Multiple SclerosisUnited States · Argentina · Australia - Ongoing, recruitingTherapeutic confirmatory (Phase III)
An Open-Label, Rater-Blind, Randomized, Multi-Center, Parallel-Arm, Active-Comparator Study to Assess the Efficacy and Tolerability of Ofatumumab 20mg SC monthly vs. First Line DMT - physician’s choice in the treatment of newly diagnosed RMS (STHENOS)
This study is testing a new way to treat multiple sclerosis (MS) called ofatumumab. It compares this new treatment to standard MS medications in people recently diagnosed with a specific type of MS called relapsing multiple sclerosis (RMS). The aim is to see which treatment works best to prevent MS attacks and stop the disease from getting worse.
For: relapsing multiple sclerosis (RMS)France · Germany · Italy - AuthorisedTherapeutic confirmatory (Phase III)
DESIRE MS: A prospective randomized non-inferiority trial comparing anti-CD20 maintenance versus De-Escalation Strategy In Relapsing-Remitting Multiple Sclerosis
This study compares different treatments for multiple sclerosis (MS) to see if a less intense approach is just as good as current treatments. It looks at how well people's MS is controlled over three years and checks for new symptoms or changes in brain scans.
For: Multiple sclerosisFrance