- AuthorisedTherapeutic exploratory (Phase II)
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Evaluating the Safety and Efficacy of PPV-06 Active Immunotherapy in Patients with Inflammatory Knee Osteoarthritis (KOA).
This study is testing a new treatment, PPV-06, for knee osteoarthritis. It aims to see if this treatment can reduce pain and improve movement compared to a dummy treatment, called a placebo, over 54 weeks.
For: Knee osteoarthritisRomania · Poland · France - Ongoing, recruitingTherapeutic exploratory (Phase II)
A placebo-controlled, double-blinded, randomized, dose-finding trial using a combination of apocynin and paeonol (APPA) for the treatment of knee osteoarthritis
This study is testing a new combination medicine (APPA) for knee osteoarthritis. Researchers want to see if APPA can reduce knee pain better than a dummy treatment or a common painkiller like Panodil. They will mostly look at how much pain changes over 12 weeks.
For: Knee osteoarthritisDenmark - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Randomized, Double-Blind, Multi-Center, Placebo-Controlled, Trial to Evaluate the Efficacy and Safety of Once Daily Diclofenac Gel AMZ001 3.06% in the Treatment of Pain and Symptoms of Knee Osteoarthritis
This study is testing a new gel (AMZ001) for knee osteoarthritis pain. Doctors want to see if it works better than a dummy gel and how safe it is. It's a key stage before the gel potentially becomes widely available.
For: Knee OsteoarthritisDenmark · Czechia · Poland