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A 2-stage, Adaptive, Randomised, Double-blind, Placebo-controlled, Multicentre Study to Evaluate Dose and Treatment Effect of Pentosan Polysulfate Sodium Compared with Placebo in Participants with Knee Osteoarthritis Pain

This study is testing a new medicine, pentosan polysulfate sodium, for knee osteoarthritis pain. Researchers want to see if it helps reduce pain and improve how well people can move their knee, compared to a dummy medicine.