- Ongoing, recruitingTherapeutic exploratory (Phase II)
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study with a Long-Term Extension Treatment Period to Assess the Efficacy and Safety of JNJ-63733657, an Anti-tau Monoclonal Antibody, in Participants with Early Alzheimer's Disease
This study is testing a new medicine, JNJ-63733657, for people with early Alzheimer's disease. Researchers want to see if it's safe and helps improve memory and thinking over two years, compared to a dummy drug.
For: Early Alzheimer's DiseaseSweden · France · Belgium - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3 Study of the Efficacy, Safety, and Pharmacokinetics of Ustekinumab as Open-label Intravenous Induction Treatment Followed by Randomized Double-blind Subcutaneous Ustekinumab Maintenance in Pediatric Participants with Moderately to Severely Active Crohn’s Disease
This study is looking at a medicine called Stelara for children and teenagers with Crohn's disease. It wants to see if Stelara helps them feel better and stay well. Participants will first receive the medicine through a drip, and then by an injection under the skin.
For: Moderately to Severely Active Crohn's DiseaseHungary · Germany · Belgium - Ongoing, recruitingTherapeutic confirmatory (Phase III)
The effect of sertraline on anxiety-depressive symptoms, endothelial dysfunction and biomarkers in heart failure patients with preserved ejection fraction
This study is looking at whether a common medicine called sertraline can help people with heart failure who also feel anxious or down. It aims to see if sertraline can improve their well-being and reduce the chances of them needing to go to the hospital or having other serious health problems.
For: Depressive-anxiety states in people with heart failure with preserved ejection fractionPoland - Ongoing, recruitingTherapeutic confirmatory (Phase III)
The efficacy and safety of Metoprolol as add-on treatment to standard of care in preventing cardiomyopathy in patients with Duchenne Muscular Dystrophy aged 8-17 years. A randomized, double-blind, placebo controlled study
This study looks at whether a medicine called Metoprolol can help prevent heart problems in young people with Duchenne Muscular Dystrophy. It compares Metoprolol to a dummy medicine to see if it makes a difference to heart strength.
For: Duchenne muscular dystrophy · Cardiomyopathy · TachycardiaPoland