- Ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2 study to assess the efficacy and safety of 2 dosage regimens of oral fidrisertib (IPN60130) for the treatment of fibrodysplasia ossificans progressiva in male and female paediatric and adult participants.
This study is testing a new medicine, fidrisertib, for children and adults with Fibrodysplasia Ossificans Progressiva (FOP). We want to see if it can slow down the new bone growth and reduce flare-ups, and if it's safe to use. Some participants will receive a dummy pill (placebo).
For: Fibrodysplasia Ossificans ProgressivaSweden · Germany · France - Ongoing, recruitingTherapeutic confirmatory (Phase III)
Personalized Vitamin D Supplementation for Reducing or Preventing Fatigue and Enhancing Quality of Life of Patients with Colorectal Tumor: Randomized Intervention Trial (VICTORIA)
This study looks at whether a personalised vitamin D supplement can help reduce tiredness and improve daily life for people with bowel cancer. It's for those who have finished treatment within the last year and have low vitamin D levels.
For: Fatigue in patients with colorectal cancer (CRC) (ICD codes C18-C20 and C21.8) within 12 months after a colorectal cancer therapy (surgery · chemotherapy and/or radiation) and not optimal vitamin D status (25-hydroxyvitamin D (25(OH)D) levels < 60 nmol/L)Germany - Active not recruitingPHASE3
Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis
This study looks at how safe and effective two medicines, fingolimod and interferon beta-1a, are for young people aged 10-17 with multiple sclerosis (MS). It compares them to see which works best and is safest.
For: Multiple SclerosisUnited States · Australia · Austria - RecruitingPHASE2, PHASE3
Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial
This study, called MND-SMART, is testing different medicines to see if they can slow down Motor Neurone Disease (MND) and help people live longer. It's designed to be flexible, quickly adding new promising drugs and removing those that don't help.
For: Motor Neuron Disease, Amyotrophic Lateral SclerosisUnited Kingdom