- RecruitingPHASE3
A Study Assessing the Effect of Dupilumab on Inducing Clinical Remission in Asthma
This study looks at whether a new asthma medicine, dupilumab, can help people with moderate asthma achieve full control earlier. It aims to prevent severe asthma by treating high-risk patients before their condition gets worse, potentially changing how asthma is managed.
For: Asthma ControlAustralia · Canada · United Kingdom - Active not recruitingPHASE3
Phase III Study of AK112 for NSCLC Patients
This study looks at a new drug, AK112, combined with standard chemotherapy for a type of lung cancer. It's for people whose cancer has progressed after previous targeted treatment. We want to see if this combination gives better results than chemotherapy alone.
For: Non-Squamous Non-small Cell Lung CancerUnited States · Canada · France - Ongoing, recruitingTherapeutic confirmatory (Phase III)
ISIS 678354-CS6 A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Patients with Severe Hypertriglyceridemia
This study is testing a new medicine, Olezarsen, for people with very high levels of a type of fat in their blood called triglycerides. We want to see if it helps lower these levels and prevent related health problems.
For: Severe hypertryglyceridemiaFrance · Italy · Hungary - Ongoing, recruitingTherapeutic confirmatory (Phase III)
J1I-MC-GZBK: A Master Protocol to Investigate the Efficacy and Safety of LY3437943 Once Weekly in Participants with Type 2 Diabetes Mellitus Who Have Obesity or Overweight: A Randomized Double-Blind, Placebo-Controlled Trial (TRIUMPH-2)
This study is looking into a new weekly injection called Retatrutide. It's for people with type 2 diabetes who are also overweight or obese. The main goal is to see how well it helps with weight loss compared to a dummy injection (placebo).
For: Type 2 Diabetes · Obesity · OverweightSpain · Romania - Ongoing, recruitingTherapeutic confirmatory (Phase III)
J1I-MC-GZBM: A Randomized, Double-Blind, Phase 3 Study to Investigate the Efficacy and Safety of LY3437943 Once Weekly Compared to Placebo in Participants with Severe Obesity and Established Cardiovascular Disease (TRIUMPH-3)
This study is looking into a new weekly injection called Retatrutide. We want to see if it helps people with severe obesity and heart problems lose weight safely. It's compared to a dummy injection to see how well it works.
For: Obesity · Cardiovascular DiseaseSlovakia · Hungary · Spain - Ongoing, recruitingTherapeutic confirmatory (Phase III)
J1I-MC-GZBN:A Phase 3 Study to Investigate the Efficacy and Safety of LY3437943 Once Weekly in Participants who have Obesity or Overweight and Osteoarthritis of the Knee: A Randomized, Double-Blind, Placebo-Controlled Trial
This study looks at a new weekly injection called LY3437943 to see if it helps people with knee osteoarthritis who are also overweight or obese. It aims to reduce knee pain and body weight, comparing the new drug to a dummy injection.
For: Overweight · Osteoarthritis · KneeSpain - Ongoing, recruitingTherapeutic confirmatory (Phase III)
J1I-MC-GZBJ: A Master Protocol to Investigate the Efficacy and Safety of LY3437943 Once Weekly in Participants Without Type 2 Diabetes Who Have Obesity or Overweight: A Randomized, Double-Blind, Placebo-Controlled Trial (TRIUMPH-1); J1I-MC-GOA1: Indication-Specific Appendix (ISA2) for participants with knee osteoarthritis (OA)
This study is looking at a new medicine called Retatrutide for adults who are overweight or have obesity. It also specifically looks at people with knee arthritis. The main goals are to see how much it helps with weight loss and how well it reduces knee pain.
For: Obesity · Overweight · OsteoarthritisRomania · Poland · Hungary - Ongoing, recruitingTherapeutic confirmatory (Phase III)
ISIS 678354-CS5: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of ISIS 678354 Administered Subcutaneously to Patients with Severe Hypertriglyceridemia.
This study is testing a new medicine, ISIS 678354, for people with very high levels of a type of fat in their blood called triglycerides. It aims to see if the medicine can lower these levels compared to a dummy medicine.
For: Severe Hypertriglyceridemia.Finland · Germany · Poland