- AuthorisedPhase II and Phase III (Integrated)
A Phase II/III Multicenter Randomized, Double-Blind, Placebo-Controlled, Two-Stage Adaptive Design, Platform Trial of Investigational Treatments for Primary Prevention of Disease Progression in Dominantly Inherited Alzheimer’s Disease
This study is testing new medicines for an early-onset, inherited form of Alzheimer's disease. Researchers want to see if these treatments can stop or slow down the disease before symptoms appear, by checking changes in the brain over time.
For: Dominantly Inherited Alzheimer’s Disease (DIAD)Spain · France · Germany - Active not recruitingPHASE3
A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3)
This study, called TRAILRUNNER-ALZ 3, is looking at a new medicine called Remternetug for people in the early stages of Alzheimer's disease. Researchers want to see if it can slow down memory, thinking, or daily living problems compared to a dummy drug (placebo).
For: Alzheimer's DiseaseUnited States · Australia · Canada - RecruitingPHASE2, PHASE3
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
This study is looking into a new treatment called remternetug for people who are at risk of developing a specific type of early-onset Alzheimer's disease due to their genes. It aims to see if the treatment can slow down or stop the disease before symptoms appear.
For: Alzheimers Disease · Dementia · Alzheimers Disease, FamilialUnited States · Argentina · Australia