- AuthorisedTherapeutic confirmatory (Phase III)
RIFAMAB : Rifabutin versus rifampicin for treatment of staphylococcal prosthetic joint infection treated with debridement, antibiotics and implant retention (DAIR strategy): a multicenter randomized, open-label, non-inferiority trial
This study compares two antibiotics, rifabutin and rifampicin, for treating joint infections caused by bacteria after surgery. It looks at how well they work to prevent further problems after a procedure called DAIR, which cleans the infection without removing the whole joint.
For: Adult with an staphylococcal prosthetic joint infection treated with debridement · antibiotics and implant retention (DAIR strategy)France - AuthorisedTherapeutic confirmatory (Phase III)
Rifampin-free regimen versus rifampin-containing regimen in the treatment of staphylococcal prosthetic valve endocarditis: a multicenter randomized controlled non-inferiority study (RIFREE)
This study compares two ways to treat a serious heart infection called staphylococcal endocarditis, which affects artificial heart valves. It looks at whether treatment without a medicine called rifampin is as good as treatment with it, focusing on patient survival after six months.
For: staphylococcal endocarditisFrance