- RecruitingTherapeutic exploratory (Phase II)
FLUOPANC II: A performance study of SGM-101, a fluorochrome-labeled anti-carcinoembryonic antigen monoclonal antibody for fluorescence-guided imaging to determine local extent and resectability during surgical resection of pancreatic ductal adenocarcinoma after neoadjuvant treatment.
This study looks at a special dye called SGM-101 to help surgeons see pancreatic cancer more clearly during an operation. It aims to improve how doctors find and remove all the cancer, especially after other treatments have been given.
For: Pancreatic tumorNetherlands - RecruitingTherapeutic exploratory (Phase II)
Focus Green: Fluorescence-guided resection Of Colorectal liver metastases Using SGM-101 and Indocyanine GREEN
This study looks at new ways to find and remove bowel cancer that has spread to the liver. It uses special dyes and imaging during surgery to help surgeons see cancer cells more clearly and make sure all of them are removed, improving treatment.
For: colorectal livermetastasesNetherlands - RecruitingTherapeutic exploratory (Phase II)
SGM-T1: SGM-101 tumor targeted fluorescence endoscopy in rectal polyps with suspected T1 adenocarcinoma or high grade dysplasia
This study tests a glowing dye called SGM-101. Doctors want to see if it helps them spot early bowel cancer or severe abnormal cells in rectal polyps. The dye makes cancer cells light up under a special camera, helping doctors see the growth clearly and remove it completely.
For: Early rectal cancerNetherlands - RecruitingTherapeutic exploratory (Phase II)
SGM-CBM: A feasibility study of SGM-101, a fluorochrome-labeled anti-carcinoembryonic antigen monoclonal antibody for the intraoperative detection of colorectal brain metastases.
This study is testing a special glowing dye called SGM-101. It is designed to help brain surgeons see and remove bowel cancer that has spread to the brain. Researchers want to find out if the dye safely highlights cancer cells during surgery, helping doctors spot tumours more clearly.
For: Brain metastasesNetherlands - RecruitingPHASE3
Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer
This study is testing a new way to help surgeons see bowel cancer more clearly during operations. It compares a special dye, SGM-101, with standard viewing methods to find cancer cells in and around the bowel.
For: Colorectal NeoplasmsUnited States · Germany · Italy