SODIUM CHLORIDE SOLUTION 0.9% clinical trials
9 indexed studies · 0 currently recruiting
- Ongoing, recruitingTherapeutic confirmatory (Phase III)
Prospective, randomised, placebo-controlled study of polyvalent intravenous immunoglobulins for the treatment of primary Sjögren's syndrome associated painful sensory neuropathies
This study looks at treating painful nerve damage in people with Sjögren's syndrome. It tests a medicine called Privigen against a dummy treatment to see if it reduces pain and improves daily life.
France - Ongoing, recruitingPhase I and Phase II (Integrated)- Other
A Phase 1b/2, Double-Blind, Placebo-Controlled, Randomized, Parallel-Arm Study to Explore Safety, Pharmacokinetics, and Early Clinical Signal of Efficacy of DS-2325a in Patients with Netherton Syndrome
This study is testing a new medicine, DS-2325a, for Netherton Syndrome. It's looking at how safe it is, how the body uses it, and if it shows early signs of helping. Patients will either get the medicine or a placebo (dummy medicine).
For: Netherton's SyndromeFrance - Ongoing, recruitingTherapeutic exploratory (Phase II)
J4E-MC-IMMB: A Master Protocol for Randomized, Controlled, Phase 2 Clinical Trials of Multiple Interventions for the Treatment of Adults with Moderate-to-Severe Atopic Dermatitis; J4E-MC-FR01: A Phase 2, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, 52-Week Study to Evaluate the Efficacy and Safety of LY3454738 in the Treatment of Adult Patients with Moderate-to-Severe Atopic Dermatitis
This study is looking into new ways to treat adults with moderate to severe eczema (atopic dermatitis). Researchers want to see how well a new medicine, LY3454738, works and if it's safe. They will compare it to a dummy treatment over 52 weeks.
For: Atopic dermatitisItaly · Poland · Hungary - Ongoing, recruitingHuman Pharmacology (Phase I)- Other
A Phase 1, Randomized, Observer-blind, Placebo-controlled, Age De-escalation Study of the Safety, Tolerability, and Immunogenicity of mRNA-1345 and mRNA-1365 in Participants Aged 5 months to < 24 months
This study is looking at how safe new vaccines are for babies aged 5 to 23 months. It's testing two different vaccines (mRNA-1345 and mRNA-1365) to see if they help protect against chest infections, like those caused by RSV. Scientists are checking for any side effects and how well the vaccines boost the babies' immune systems.
For: Acute lower respiratory infectionSpain · Latvia · Poland - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2, Multicenter, Randomized, Double-blind, Placebo‑controlled Study with Deferred Active Treatment to Investigate the Efficacy, Safety, and Pharmacokinetics of JNJ‑73763989 + Nucleos(t)ide Analog in Participants Co‑infected with Hepatitis B and Hepatitis D Virus
This study is looking into a new treatment, JNJ-73763989, for people who have both Hepatitis B and Hepatitis D. It aims to see how well it works, if it's safe, and how the body handles it, compared to a dummy treatment.
For: Hepatitis B and Hepatitis D Viral Co-infectionSweden · Italy · France - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2, Randomized, Observer-Blind, Placebo-Controlled, Dose-Escalation Study to Evaluate the Reactogenicity, Safety, and Immunogenicity of mRNA-1345, an mRNA Vaccine Targeting Respiratory Syncytial Virus, in Pregnant Women, and Safety, and Immunogenicity in Infants Born to Vaccinated Mothers.
This study is testing a new vaccine for pregnant women to protect their babies from RSV, a common chest infection. We're looking at how safe the vaccine is, its side effects, and how well it helps the mother and baby fight off RSV.
For: Respiratory syncytial virusDenmark - Ongoing, recruitingTherapeutic confirmatory (Phase III)
C4601003 - A PHASE 3, MULTICENTER, PLACEBO-CONTROLLED, RANDOMIZED, OBSERVER-BLINDED TRIAL TO EVALUATE THE EFFICACY, SAFETY, TOLERABILITY, IMMUNOGENICITY, AND LOT CONSISTENCY OF A 6-VALENT OSPA-BASED LYME DISEASE VACCINE IN HEALTHY PARTICIPANTS ≥5 YEARS OF AGE
This study is testing a new vaccine to see if it can prevent Lyme disease. Researchers want to find out how well it works, if it's safe for people aged 5 and older, and if it causes any side effects. They are also checking how the body reacts to the vaccine.
For: Active immunization against Lyme diseaseSweden · Netherlands · Poland - AuthorisedTherapeutic confirmatory (Phase III)
Immediate post-surgical Botulinum toxin injections to prevent dystrophic Scars after sternotomy : a placebo-controlled randomized clinical trial - BotuCiSter
This study looks at whether a Botox injection given right after heart surgery (a sternotomy) can help reduce the appearance of scars. Half the scar gets Botox, and the other half gets a non-active solution, to see which looks better after 6 months.
For: Surgery with sternotomyFrance - AuthorisedTherapeutic exploratory (Phase II)
Methotrexate treatment in hand osteoarthritis refractory to usual treatments: A randomised, double-blind, placebo-controlled trial, ADEM2 study
This study looks at whether a medicine called methotrexate can help people with severe hand osteoarthritis that hasn't improved with other treatments. It specifically focuses on an aggressive type of hand osteoarthritis where joints get damaged. Researchers want to see if methotrexate can slow down this damage.
For: Erosive osteoarthritisFrance