- AuthorisedTherapeutic exploratory (Phase II)
Efficacy of psilocybin and trazodone combination in treatment-resistant depression: a randomized controlled proof-of-concept study (PSILOTRAZ)
This study is looking into whether a combination of psilocybin and trazodone can help people with depression that hasn't responded to other treatments. Researchers want to see if this new approach can improve mood and reduce depression symptoms.
For: Treatment-resistant depressionFrance - Ongoing, recruitingTherapeutic exploratory (Phase II)
Randomized, multicentre phase II trial of the sequencing of Radium-223 and Docetaxel plus prednisone in symptomatic bone-only metastatic castration-resistant prostate cancer (mCRPC)
This study is looking at how best to give two common treatments, Radium-223 and Docetaxel, for prostate cancer that has spread to the bones. It compares different ways of giving these treatments to see which works best for improving quality of life and managing pain.
For: metastatic castration resistant prostate cancer (mCRPC) · symptomatic bone-only metastatic castration resistant prostate cancer (mCRPC)Italy - Ongoing, recruitingTherapeutic confirmatory (Phase III)
MULTICENTRE, RANDOMISED, DOUBLE-BLIND, VEHICLE AND ACTIVE-CONTROLLED PHASE III STUDY EVALUATING THE EFFICACY AND SAFETY OF KETOTIFEN OPHTHALMIC SOLUTION 0.5 MG/ML COMPARED TO VEHICLE AND KETOFTIL (KETOTIFEN OPHTHALMIC SOLUTION 0.5 MG/ML) FOR THE TREATMENT OF SEASONAL ALLERGIC CONJUNCTIVITIS.
This study is looking at a new eye drop, Ketotifen, for seasonal itchy eyes caused by allergies. It compares the new drop to a similar existing one and a dummy drop to see how well it works and if it's safe for adults.
For: SEASONAL ALLERGIC CONJUNCTIVITISItaly