- Ongoing, recruitingTherapeutic confirmatory (Phase III)
COTRIVAP - Efficacy of cotrimoxazole as a de-escalation treatment of Ventilator-Associated Pneumonia in intensive care unit. Multicentric non-inferiority randomised controlled trial
This study is looking at whether a common antibiotic, co-trimoxazole, can be used to treat pneumonia in patients on a ventilator in intensive care. It compares it to standard treatments to see if it works just as well and is safe.
For: Intensive Care · Ventilator-associated PneumoniaFrance - Ongoing, recruitingTherapeutic confirmatory (Phase III)
Temocillin versus meropenem for the targeted treatment of bacteraemia due to third-generation cephalosporin-resistant Enterobacterales (ASTARTÉ):randomised, pragmatic trial
This study compares different antibiotics (temocillin, meropenem, ertapenem) to treat serious blood infections caused by specific bacteria that are hard to treat. It aims to find the best antibiotic that helps patients get better, stay alive, and avoid long treatments or side effects.
For: Infections due to EnterobacteriaceaeSpain