Temozolomide (TMZ) clinical trials
4 indexed studies · 3 currently recruiting
- RecruitingPHASE2
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
This study is looking at new drug combinations to treat certain types of brain tumours in children and young adults. It aims to see if combining ribociclib with either everolimus or temozolomide can help patients live longer and improve their health.
For: High Grade Glioma · Diffuse Intrinsic Pontine Glioma · Anaplastic AstrocytomaUnited States · Australia · Canada - Active not recruitingPHASE1, PHASE2
Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma
This study looks at a new drug, Vorasidenib, with a standard cancer drug, Temozolomide (TMZ), for a type of brain tumour called glioma. It aims to check if this combination is safe and how well it works.
For: IDH1-mutant Glioma · IDH2-mutant GliomaUnited States · Austria · China - RecruitingPHASE1, PHASE2
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
This study tests a new drug, AZD9574, alone and with other treatments, for people with advanced cancers. It aims to see how safe it is, how the body handles it, and if it helps shrink tumours.
For: Advanced Solid MalignanciesUnited States · Australia · Germany - RecruitingPHASE1, PHASE2
A Multi-Arm, Platform Trial For Relapsed Neuroblastoma
This study looks for better ways to treat neuroblastoma in children and young people when it comes back. It tests new drug combinations to improve survival and quality of life for patients and to understand the disease better.
For: Relapsed NeuroblastomaAustralia · Austria · Belgium