Tenofovir alafenamide clinical trials
5 indexed studies · 0 currently recruiting
- Active not recruitingPHASE3
A Study to Evaluate the Efficacy, Safety, and Tolerability of Using an Oral Once-daily 2 Drug Regimen Compared to an Oral Once-daily 3 Drug Regimen for the Treatment of Human Immunodeficiency Virus (HIV)-1 in Adults Who Have Not Previously Taken Antiretroviral Therapy
This study looks at two different daily pill combinations for adults newly diagnosed with HIV. It compares a two-drug treatment with a three-drug treatment to see which is safer and works better for controlling the virus.
For: HIV · HIV InfectionsArgentina · Belgium · Denmark - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2, Multicenter, Randomized, Double-blind, Placebo‑controlled Study with Deferred Active Treatment to Investigate the Efficacy, Safety, and Pharmacokinetics of JNJ‑73763989 + Nucleos(t)ide Analog in Participants Co‑infected with Hepatitis B and Hepatitis D Virus
This study is looking into a new treatment, JNJ-73763989, for people who have both Hepatitis B and Hepatitis D. It aims to see how well it works, if it's safe, and how the body handles it, compared to a dummy treatment.
For: Hepatitis B and Hepatitis D Viral Co-infectionSweden · Italy · France - Ongoing, recruitingTherapeutic exploratory (Phase II)
An open-label, non-randomized, biopsy-based mechanistic study on pharmacokinetics, pharmacodynamics, safety and tolerability of ianalumab in patients with Sjögren's syndrome
This study is looking at a new medicine called ianalumab for Sjögren's syndrome. We want to see how it affects cells in the salivary glands, how safe it is, and how the body uses it. This is an early-stage study.
For: Sjögren's syndromeFrance - Ongoing, recruitingTherapeutic confirmatory (Phase III)
The Italian Cohort (ITACO) and the Analytical Antiretroviral Treatment Interruption Italian Cohort (ITACO-ATI) study guided by molecular HIV-1 reservoir profiling
This study looks at HIV in people who got it at birth. It's trying to find new ways to understand how the virus hides in the body and if some people can safely stop their HIV medicine under close medical watch.
For: perinatally HIV infectionItaly - AuthorisedTherapeutic exploratory (Phase II)
TARGET-EBV in MS: A prospective randomized controlled parallel group phase 2b double blinded study to investigate if targeting Epstein Barr Virus with Tenofovir Alafenamide Fumarate compared to placebo as add-on treatment to anti-CD20 therapy reduces neuronal damage in multiple sclerosis
This study looks into whether a drug called Tenofovir Alafenamide, given alongside a standard MS treatment, can help reduce nerve damage in people with multiple sclerosis by targeting the Epstein-Barr virus. It compares the drug to a dummy pill.
For: multiple sclerosisNorway