- Active not recruitingPHASE3
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)
This study is looking at a new medicine called remibrutinib for people with relapsing multiple sclerosis (RMS). It compares remibrutinib to an existing medicine, teriflunomide, to see how well it works and if it's safe. It's a large study, involving about 800 people.
For: Relapsing Multiple SclerosisUnited States · Argentina · Brazil - Active not recruitingPHASE3
Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)
This study is looking at a new medicine called fenebrutinib for people with a type of multiple sclerosis (MS) called relapsing MS. It compares fenebrutinib to an existing medicine, teriflunomide, to see if it works better and is safe.
For: Relapsing Multiple SclerosisUnited States · Austria · Brazil - Active not recruitingPHASE3
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)
This study is comparing a new medication called remibrutinib with an existing treatment, teriflunomide, for people with relapsing multiple sclerosis (RMS). It aims to see how well remibrutinib works and if it's safe to use in managing RMS symptoms.
For: Relapsing Multiple SclerosisUnited States · Argentina · Austria - Active not recruitingPHASE3
A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.
This study looks at the everyday safety and how well a drug called tolebrutinib is tolerated over a long time. It's for adults with different types of multiple sclerosis (MS) who have already been in earlier tolebrutinib studies.
For: Relapsing Multiple Sclerosis · Secondary Progressive Multiple Sclerosis · Progressive Relapsing Multiple SclerosisUnited States · Argentina · Australia - Ongoing, recruitingTherapeutic confirmatory (Phase III)
An Open-Label, Rater-Blind, Randomized, Multi-Center, Parallel-Arm, Active-Comparator Study to Assess the Efficacy and Tolerability of Ofatumumab 20mg SC monthly vs. First Line DMT - physician’s choice in the treatment of newly diagnosed RMS (STHENOS)
This study is testing a new way to treat multiple sclerosis (MS) called ofatumumab. It compares this new treatment to standard MS medications in people recently diagnosed with a specific type of MS called relapsing multiple sclerosis (RMS). The aim is to see which treatment works best to prevent MS attacks and stop the disease from getting worse.
For: relapsing multiple sclerosis (RMS)France · Germany · Italy - Active not recruitingPHASE3
Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis
This study is looking at a new medicine called frexalimab for people aged 18-55 with certain types of Multiple Sclerosis (MS). It compares frexalimab to an existing MS medicine, teriflunomide, to see how well it stops MS relapses and if it's safe.
For: Multiple SclerosisUnited States · Argentina · Austria - AuthorisedTherapeutic confirmatory (Phase III)
DESIRE MS: A prospective randomized non-inferiority trial comparing anti-CD20 maintenance versus De-Escalation Strategy In Relapsing-Remitting Multiple Sclerosis
This study compares different treatments for multiple sclerosis (MS) to see if a less intense approach is just as good as current treatments. It looks at how well people's MS is controlled over three years and checks for new symptoms or changes in brain scans.
For: Multiple sclerosisFrance