- CompletedPhase II
Tranexamic acid to prevent anastomotic leak after rectal cancer surgery
This study looks at whether a medicine called tranexamic acid can stop bowel joins from leaking after rectal cancer surgery. During surgery, doctors place a soft tube to give either the medicine or sterile water directly into the back passage for three days to see if it aids healing.
For: Anastomotic leak; rectal cancer surgeryUnited Kingdom · England - RecruitingTherapeutic use (Phase IV)
“Randomized, double-blind clinical trial to assess the efficacy of tranexamic acid in reducing blood loss in patients with hip fracture”.
This study looks at whether a medicine called tranexamic acid can reduce blood loss in adults having surgery for a broken hip. Researchers want to see if the treatment lowers the need for blood transfusions and helps patients recover safely both in hospital and over the following year.
For: Hip fractureSpain - RecruitingPHASE3
Tranexamic Acid for Reduction of Transfusion in Abdominal Surgery
This study looks at whether a medicine called tranexamic acid can reduce the need for blood transfusions during or after major tummy surgery. Researchers want to know if it's safe and effective in preventing significant blood loss.
For: Surgical Blood Loss · Transfusion-dependent Anemia · Abdomen DiseaseGermany - RecruitingNA
Tranexamic Acid Use on Pain, Mobility and Bleeding Following Total Hip and Total Knee Arthroplasty
This study is comparing different ways of giving tranexamic acid (TXA) after hip or knee replacement surgery. TXA is a medicine used to reduce bleeding after operations. We want to see if extra doses given by mouth help with pain, moving around, and how much you bleed.
For: Postoperative BleedingCanada - RecruitingPHASE2
Evaluation of Tranexamic Acid in Myelodysplastic Syndromes and Acute Myeloid Leukemia
This study looks at whether a medicine called tranexamic acid can help stop bleeding in people with certain blood cancers like MDS and AML. Some patients will get the medicine, others a dummy pill. We want to see if it safely reduces bleeding problems.
For: Myelodysplastic Syndromes · Acute Myeloid Leukemia · Myelodysplastic/Myeloproliferative NeoplasmCanada - RecruitingPHASE1, PHASE2
Treatment of Nosebleeds in the Emergency Department With Powder Tranexamic Acid
This study is testing a new way to treat nosebleeds using a powder spray. It's looking to see if spraying tranexamic acid directly into the nose can stop bleeding and be a gentler option than current methods like burning or packing the nose.
For: Epistaxis NosebleedCanada