- RecruitingPHASE3
Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)
This study looks at a medicine called tulisokibart for Crohn's disease and ulcerative colitis. It's for people who were in earlier trials and found benefit from it. The aim is to check its long-term safety and how well it works over time.
For: Crohn Disease · Colitis, UlcerativeUnited States · Czechia · France - RecruitingPHASE2
A Clinical Study of Tulisokibart (MK-7240) to Treat Rheumatoid Arthritis (RA) (MK-7240-014)
This study is testing a new medicine, tulisokibart, for people with rheumatoid arthritis (RA) whose current treatment with methotrexate isn't enough. Researchers want to see if this new medicine, given in different doses, can reduce RA symptoms better than a dummy medicine.
For: Arthritis, RheumatoidUnited States · Canada · Chile - Active not recruitingPHASE2
Study to Evaluate Tulisokibart for Hidradenitis Suppurativa (MK-7240-012)
This study is looking into a new medication called tulisokibart for people with moderate to severe hidradenitis suppurativa (HS). It aims to see if this new treatment is better than a dummy medicine (placebo) at reducing HS symptoms over 16 weeks.
For: Hidradenitis SuppurativaUnited States · Argentina · Australia - RecruitingPHASE2
A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)
This study is looking for a new way to treat a type of arthritis called radiographic axial spondyloarthritis (r-axSpA). Researchers want to see if an experimental medicine, tulisokibart, can help reduce pain, stiffness, and swelling in the spine and hips for people with this condition.
For: Radiographic Axial SpondyloarthritisUnited States · Brazil · Canada - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2a, Multi-Center, Open-Label Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of PRA023 in Subjects with Moderately to Severely Active Crohn’s Disease
This study is looking at a new medicine called tulisokibart for people with Crohn's disease. We want to see if it's safe, how well it works, and how the body handles it. It's an early-stage study to understand its potential.
For: Crohn's diseaseFrance · Poland · Czechia - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2, Multi-Center, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Induction Therapy with PRA023 in Subjects with Moderately to Severely Active Ulcerative Colitis
This study is looking into a new medicine called tulisokibart for people aged 18 and over with moderate to severe ulcerative colitis. It aims to see if the medicine is safe and helps to reduce symptoms like stomach pain and bleeding, compared to a dummy treatment.
For: Ulcerative ColitisCzechia · Poland · France - Active not recruitingPHASE2
Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Systemic Sclerosis Associated With Interstitial Lung Disease (SSc-ILD) (MK-7240-007)
This study looks at a new drug, tulisokibart, for people with a lung condition called interstitial lung disease (ILD) linked to scleroderma. We want to see if it's safe and helps improve the condition.
For: Diffuse Cutaneous Systemic Sclerosis · Interstitial Lung DiseaseUnited States · Argentina · Australia