- Active not recruitingPHASE2, PHASE3
An International, Multicenter, Randomized, Double-Blind, Parallel Group, Vehicle-Controlled, Phase 2/3 Study With Open-Label Extension Evaluating the Efficacy and Safety of Diacerein 1% Ointment for the Treatment of Generalized Epidermolysis Bullosa Simplex (EBS)
This study tests a special cream (AC-203) for a skin condition called Epidermolysis Bullosa Simplex (EBS). It looks at how well the cream works to reduce blistering and how safe it is for people with widespread EBS, including children.
For: Generalized Epidermolysis Bullosa SimplexUnited States · Australia · Austria - RecruitingPHASE3
An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED
This study is looking into a new eye drop called cenegermin to treat a persistent sore on the front of the eye (cornea). Researchers want to see if it helps the sore heal better and if it's safe compared to a dummy treatment. It involves different treatment and follow-up periods.
For: Persistent Corneal Epithelial DefectUnited States · Argentina · Czechia - RecruitingPHASE3
Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)
This study is looking at a nasal spray medicine called Cenegermin for adults with a sudden vision problem called NAION. It wants to see if this new treatment can help improve vision and if it's safe to use. Half the people will get the medicine, and half will get a dummy spray.
For: Non-Arteritic Anterior Ischemic Optic NeuropathyUnited States · Australia · United Kingdom